SCHEMBL30489259

SCHEMBL30489259

Oc1cccc(C(=C(c2ccccc2)c2ccccc2)c2ccccc2)c1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 6/20 0.46
ALDH1A1 P00352 4/20 0.46
LMNA P02545 4/20 0.46
CA2 P00918 3/20 0.46
ALOX15 P16050 3/20 0.46
HSD17B10 Q99714 3/20 0.46
CA1 P00915 2/20 0.46
CA6 P23280 2/20 0.46
EGFR P00533 2/20 0.46
FYN P06241 2/20 0.46
MMP9 P14780 2/20 0.46
RECQL P46063 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
ADAMTS4 O75173 1/20 0.46
MMP2 P08253 1/20 0.46
MMP8 P22894 1/20 0.46
CDK2 P24941 1/20 0.46
MMP12 P39900 1/20 0.46
ADAMTS5 Q9UNA0 1/20 0.46
KDM4E B2RXH2 5/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28175701 1.00 HPGD (0.46) HPGDALDH1A1LMNACA2ALOX15
SCHEMBL25377096 0.89 HPGD (0.44) HPGDALDH1A1LMNACA2ALOX15
SCHEMBL7124543 0.84 HPGD (0.52) HPGDALDH1A1LMNACA2ALOX15
SCHEMBL1004754 0.78 HPGD (0.46) HPGDALDH1A1LMNACA2ALOX15
SCHEMBL308224 0.78 HPGD (0.46) HPGDALDH1A1LMNACA2ALOX15
Catechol SCHEMBL28725249 0.78 ALDH1A1 (0.62) HPGDALDH1A1LMNACA2ALOX15
SCHEMBL29767790 0.77 GAA (0.58) HPGDALDH1A1LMNACA2ALOX15
SCHEMBL147459 0.77 GAA (0.58) HPGDALDH1A1LMNACA2ALOX15
SCHEMBL11145321 0.75 GAA (0.56) HPGDALDH1A1LMNACA2ALOX15
SCHEMBL6652372 0.75 GAA (0.56) HPGDALDH1A1LMNACA2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118420882-B Polymer containing tetraphenyl ethylene and mannose in side chain, preparation method and application thereof 上海美迪西生物医药股份有限公司 2024-09-27 CN claimed
CN-118406174-B Mannose-containing polymer, method for preparing mannose-containing polymer by combining RAFT polymerization and click chemistry and application thereof 上海美迪西生物医药股份有限公司 2024-08-30 CN claimed
CN-118420882-A Polymer containing tetraphenyl ethylene and mannose in side chain, preparation method and application thereof 上海美迪西生物医药股份有限公司 2024-08-02 CN claimed
CN-118406174-A Mannose-containing polymer, method for preparing mannose-containing polymer by combining RAFT polymerization and click chemistry and application thereof 上海美迪西生物医药股份有限公司 2024-07-30 CN claimed
CN-115096864-B Application of AIE molecule as probe in detection of carbon material negative electrode 清华大学 2025-02-11 CN disclosed
CN-118420882-B Polymer containing tetraphenyl ethylene and mannose in side chain, preparation method and application thereof 上海美迪西生物医药股份有限公司 2024-09-27 CN disclosed
CN-118406174-B Mannose-containing polymer, method for preparing mannose-containing polymer by combining RAFT polymerization and click chemistry and application thereof 上海美迪西生物医药股份有限公司 2024-08-30 CN disclosed
CN-118420882-A Polymer containing tetraphenyl ethylene and mannose in side chain, preparation method and application thereof 上海美迪西生物医药股份有限公司 2024-08-02 CN disclosed
CN-118406174-A Mannose-containing polymer, method for preparing mannose-containing polymer by combining RAFT polymerization and click chemistry and application thereof 上海美迪西生物医药股份有限公司 2024-07-30 CN disclosed
CN-116478097-A Porous material with adsorption and fluorescence characteristics as well as preparation method and application thereof 西南科技大学 2023-07-25 CN disclosed