Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 13/20 | 0.46 |
| ▸ | BCL2 | P10415 | 13/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 7/20 | 0.44 |
| ▸ | BCL2L2 | Q92843 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1955748 | 0.85 | BCL2L1 (0.59) | BCL2L1BCL2MCL1MAPTMAPK1 | |
| SCHEMBL30112805 | 0.82 | BCL2L1 (0.46) | BCL2L1BCL2MCL1FBP1 | |
| SCHEMBL29855685 | 0.80 | BCL2L1 (0.58) | BCL2L1BCL2MCL1BCL2L2 | |
| SCHEMBL29777517 | 0.79 | CA12 (0.42) | MAPT | |
| SCHEMBL25214997 | 0.79 | CA12 (0.42) | MAPT | |
| SCHEMBL30112966 | 0.78 | MAPT (0.51) | BCL2L1BCL2MCL1MAPTMAPK1 | |
| SCHEMBL30528147 | 0.78 | BCL2L1 (0.62) | BCL2L1BCL2MCL1 | |
| SCHEMBL30414565 | 0.77 | BCL2 (0.38) | BCL2L1BCL2MCL1MAPTMAPK1 | |
| SCHEMBL30921514 | 0.77 | BCL2L1 (0.45) | BCL2L1BCL2MCL1FBP1 | |
| SCHEMBL1958802 | 0.77 | BCL2L1 (0.48) | BCL2L1BCL2MCL1BCL2L2FBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116419753-A | Heterocyclic compounds as BCL-2 inhibitors | 北京诺诚健华医药科技有限公司 | 2023-07-11 | — | — | CN | disclosed |