Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 16/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 5/20 | 0.38 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.38 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.38 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.38 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30413781 | 0.92 | BCL2 (0.39) | BCL2BCL2L1MAPT | |
| SCHEMBL25224949 | 0.82 | RORC (0.36) | MAPT | |
| SCHEMBL31019217 | 0.82 | KCNH2 (0.39) | BCL2BCL2L1MAPTMAPK1 | |
| SCHEMBL30489356 | 0.77 | BCL2L1 (0.46) | BCL2BCL2L1MAPTMAPK1MCL1 | |
| SCHEMBL25219639 | 0.76 | KMT2A (0.37) | — | |
| SCHEMBL30414356 | 0.76 | KMT2A (0.37) | — | |
| SCHEMBL26444023 | 0.76 | GSTP1 (0.42) | MAPTMAPK1 | |
| SCHEMBL30112805 | 0.75 | BCL2L1 (0.46) | BCL2BCL2L1MCL1 | |
| SCHEMBL30311483 | 0.75 | MAPT (0.46) | BCL2BCL2L1MAPTMAPK1MCL1 | |
| SCHEMBL1955748 | 0.75 | BCL2L1 (0.59) | BCL2BCL2L1MAPTMAPK1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116217566-B | Anti-apoptosis protein BCL-2 inhibitor, pharmaceutical composition and application thereof | 杭州和正医药有限公司 | 2025-05-23 | — | — | CN | disclosed |
| CN-118215661-A | Compounds as BCL-2 inhibitors | 重庆复创医药研究有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-116217566-A | Anti-apoptosis protein BCL-2 inhibitor, pharmaceutical composition and application thereof | 杭州和正医药有限公司 | 2023-06-06 | — | — | CN | disclosed |