Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF4 | P18848 | 16/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22437015 | 1.00 | ATF4 (0.48) | ATF4ALDH1A1GAASMYD3 | |
| SCHEMBL22437058 | 0.92 | ATF4 (0.57) | ATF4 | |
| SCHEMBL19555818 | 0.91 | ATF4 (0.47) | ATF4 | |
| SCHEMBL19556437 | 0.88 | ATF4 (0.50) | ATF4 | |
| SCHEMBL22436941 | 0.85 | ATF4 (0.47) | ATF4ALDH1A1GAA | |
| SCHEMBL19556260 | 0.84 | ATF4 (0.50) | ATF4ALDH1A1GAA | |
| SCHEMBL19569117 | 0.83 | SMYD3 (0.47) | ATF4ALDH1A1GAASMYD3 | |
| SCHEMBL19555798 | 0.83 | KDM4E (0.52) | ATF4ALDH1A1GAA | |
| SCHEMBL19556117 | 0.83 | ATF4 (0.58) | ATF4 | |
| SCHEMBL19556284 | 0.83 | ATF4 (0.55) | ATF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3452456-B1 | BICYCLIC MODULATORS OF THE INTEGRATED STRESS PATHWAY | CALICO LIFE SCIENCES LLC (US) | 2023-07-05 | — | — | EP | disclosed |