SCHEMBL30489505

SCHEMBL30489505

Cn1c2c(c3ccc(Oc4ccc(F)cc4)cc31)CCN(C(=O)OC(C)(C)C)CC2

nearest known ligand 0.46

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ S1PR2 O95136 1/20 0.46
▸ MCHR1 Q99705 6/20 0.43
▸ HIF1A Q16665 1/20 0.41
▸ HTR5A P47898 3/20 0.38
▸ BRD3 Q15059 1/20 0.38
▸ HPGDS O60760 1/20 0.38
▸ PLK1 P53350 1/20 0.38
▸ GRM5 P41594 1/20 0.38
▸ GRM1 Q13255 1/20 0.38
▸ MEN1 O00255 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ ESR2 Q92731 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30489513 0.91 CSF1R (0.43) MCHR1HIF1AGRM5
SCHEMBL30489511 0.88 MCHR1 (0.51) MCHR1
SCHEMBL21999955 0.82 HDAC1 (0.47) MCHR1HPGDSESR2
SCHEMBL21588441 0.82 ESR2 (0.45) MCHR1BRD3HPGDSESR2
SCHEMBL25634076 0.81 MCHR1 (0.50) MCHR1HIF1AHTR5A
SCHEMBL30489504 0.81 S1PR2 (0.42) S1PR2HTR5AHPGDSGRM5GRM1
SCHEMBL1003831 0.81 USP30 (0.46) MCHR1GRM5ESR2
SCHEMBL30489508 0.80 MCHR1 (0.57) MCHR1
SCHEMBL21588362 0.78 KRAS (0.45) BRD3HPGDSPLK1ESR2
SCHEMBL5108079 0.78 BAZ2B (0.53) HTR5AHPGDSPLK1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250235463-A1 PHENOXY AND BENZYLOXY SUBSTITUTED PSYCHOPLASTOGENS AND USES THEREOF DELIX THERAPEUTICS, INC. 2025-07-24 — — US disclosed
US-12295959-B2 Phenoxy and benzyloxy substituted psychoplastogens and uses thereof DELIX THERAPEUTICS, INC. (US) 2025-05-13 — — US disclosed
EP-4448531-A1 PHENOXY AND BENZYLOXY SUBSTITUTED PSYCHOPLASTOGENS AND USES THEREOF Delix Therapeutics, Inc. (US) 2024-10-23 — — EP disclosed
US-20240335454-A1 PHENOXY AND BENZYLOXY SUBSTITUTED PSYCHOPLASTOGENS AND USES THEREOF DELIX THERAPEUTICS, INC. 2024-10-10 — — US disclosed
WO-2023114313-A1 PHENOXY AND BENZYLOXY SUBSTITUTED PSYCHOPLASTOGENS AND USES THEREOF DELIX THERAPEUTICS, INC. (US) 2023-06-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240335454-A1 PHENOXY AND BENZYLOXY SUBSTITUTED PSYCHOPLASTOGENS AND USES THEREOF GAP43, BDNF, GRIN2A S1PR2 1460/4885MCHR1 633/4885HIF1A 2997/4885
US-12295959-B2 Phenoxy and benzyloxy substituted psychoplastogens and uses thereof GAP43, BDNF, GRIN2A S1PR2 1460/4885MCHR1 633/4885HIF1A 2997/4885
US-20250235463-A1 PHENOXY AND BENZYLOXY SUBSTITUTED PSYCHOPLASTOGENS AND USES THEREOF GAP43, BDNF, GRIN2A S1PR2 1460/4885MCHR1 633/4885HIF1A 2997/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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