Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 2/20 | 0.30 |
| ▸ | CTSK | P43235 | 2/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30489650 | 1.00 | SERPINE1 (0.39) | SERPINE1MEN1GAAKMT2AHTT | |
| SCHEMBL5403745 | 0.83 | MEN1 (0.44) | SERPINE1MEN1GAAKMT2AHTT | |
| SCHEMBL25400155 | 0.79 | SERPINE1 (0.40) | SERPINE1MEN1GAAKMT2AHTT | |
| SCHEMBL30015389 | 0.79 | SERPINE1 (0.40) | SERPINE1MEN1GAAKMT2AHTT | |
| SCHEMBL6854629 | 0.79 | SERPINE1 (0.40) | SERPINE1MEN1GAAKMT2AHTT | |
| SCHEMBL25809239 | 0.78 | SERPINE1 (0.39) | SERPINE1MEN1GAAKMT2AHTT | |
| SCHEMBL25809213 | 0.78 | SERPINE1 (0.39) | SERPINE1MEN1GAAKMT2AHTT | |
| SCHEMBL26314494 | 0.78 | SERPINE1 (0.39) | SERPINE1MEN1GAAKMT2AHTT | |
| SCHEMBL20297742 | 0.78 | SERPINE1 (0.39) | SERPINE1MEN1GAAKMT2AHTT | |
| SCHEMBL20298107 | 0.77 | SERPINE1 (0.43) | SERPINE1MEN1GAAKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3313828-B1 | METALLO-BETA-LACTAMASE INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2023-07-12 | — | — | EP | disclosed |