Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.51 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GMNN | O75496 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20954203 | 1.00 | KDM4E (0.51) | KDM4EHSD17B10PDE1CALDH1A1CYP2C9 | |
| SCHEMBL30162810 | 0.92 | BACE1 (0.38) | KDM4EHSD17B10PDE1CALDH1A1TSHR | |
| SCHEMBL22400637 | 0.92 | BACE1 (0.38) | KDM4EHSD17B10PDE1CALDH1A1TSHR | |
| SCHEMBL20954328 | 0.89 | KDM4E (0.40) | KDM4EHSD17B10PDE1CALDH1A1CYP2C9 | |
| SCHEMBL20954229 | 0.89 | HSD17B10 (0.40) | KDM4EHSD17B10PDE1CALDH1A1CYP2C9 | |
| SCHEMBL30489864 | 0.89 | HSD17B10 (0.40) | KDM4EHSD17B10PDE1CALDH1A1CYP2C9 | |
| SCHEMBL30489861 | 0.89 | KDM4E (0.40) | KDM4EHSD17B10PDE1CALDH1A1CYP2C9 | |
| SCHEMBL29105646 | 0.88 | BACE1 (0.36) | KDM4EHSD17B10PDE1CALDH1A1TSHR | |
| SCHEMBL29105617 | 0.86 | KDM4E (0.46) | KDM4EHSD17B10PDE1CALDH1A1CYP2C9 | |
| SCHEMBL20954525 | 0.86 | NR3C2 (0.52) | KDM4EALDH1A1KMT2AMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111491935-B | Novel analogs as modulators of androgen and glucocorticoid receptors | 昂科斯特拉公司 | 2023-08-22 | — | — | CN | claimed |
| CN-111491935-B | Novel analogs as modulators of androgen and glucocorticoid receptors | 昂科斯特拉公司 | 2023-08-22 | — | — | CN | disclosed |