Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22400637 | 1.00 | BACE1 (0.38) | BACE1HSD17B10KDM4ENR3C2CASP1 | |
| SCHEMBL29105646 | 0.95 | BACE1 (0.36) | BACE1HSD17B10KDM4ENR3C2CASP1 | |
| SCHEMBL30489840 | 0.92 | KDM4E (0.51) | HSD17B10KDM4EPDE1CSMN1; SMN2ALDH1A1 | |
| SCHEMBL20954203 | 0.92 | KDM4E (0.51) | HSD17B10KDM4EPDE1CSMN1; SMN2ALDH1A1 | |
| SCHEMBL10375741 | 0.90 | KDM4E (0.38) | BACE1HSD17B10KDM4ECASP1PDE1C | |
| SCHEMBL20954525 | 0.87 | NR3C2 (0.52) | KDM4ENR3C2ALDH1A1MAPTMEN1 | |
| SCHEMBL20954446 | 0.86 | ADORA2B (0.45) | HSD17B10KDM4ENR3C2CASP1SMN1; SMN2 | |
| SCHEMBL20954247 | 0.86 | PDE1C (0.45) | HSD17B10KDM4ECASP1PDE1CALDH1A1 | |
| SCHEMBL20954323 | 0.86 | NR3C2 (0.51) | KDM4ENR3C2ALDH1A1MAPTMEN1 | |
| SCHEMBL30489862 | 0.86 | PDE1C (0.45) | HSD17B10KDM4ECASP1PDE1CALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111491935-B | Novel analogs as modulators of androgen and glucocorticoid receptors | 昂科斯特拉公司 | 2023-08-22 | — | — | CN | claimed |
| EP-3707143-B9 | NEW ANALOGS AS ANDROGEN RECEPTOR AND GLUCOCORTICOID RECEPTOR MODULATORS | ONCOSTELLAE S L (ES) | 2023-04-12 | — | — | EP | claimed |
| EP-3707143-B1 | NEW ANALOGS AS ANDROGEN RECEPTOR AND GLUCOCORTICOID RECEPTOR MODULATORS | ONCOSTELLAE S L (ES) | 2022-12-28 | — | — | EP | claimed |
| CN-111491935-B | Novel analogs as modulators of androgen and glucocorticoid receptors | 昂科斯特拉公司 | 2023-08-22 | — | — | CN | disclosed |