Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 5/20 | 0.44 |
| ▸ | BUB1 | O43683 | 7/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 7/20 | 0.38 |
| ▸ | ACVRL1 | P37023 | 6/20 | 0.38 |
| ▸ | ACVR1B | P36896 | 5/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30385380 | 0.95 | TYK2 (0.45) | TYK2BUB1TGFBR1ACVRL1ACVR1B | |
| SCHEMBL30490075 | 0.93 | TYK2 (0.51) | TYK2BUB1TGFBR1ACVRL1ACVR1B | |
| SCHEMBL30490068 | 0.87 | TYK2 (0.46) | TYK2BUB1JAK1CYP2C19 | |
| SCHEMBL30490066 | 0.86 | TYK2 (0.41) | TYK2BUB1TGFBR1ACVRL1ACVR1B | |
| SCHEMBL24498504 | 0.86 | TYK2 (0.46) | TYK2JAK1CYP2C19 | |
| SCHEMBL29686522 | 0.86 | TYK2 (0.46) | TYK2JAK1CYP2C19 | |
| SCHEMBL30385434 | 0.85 | TYK2 (0.42) | TYK2JAK1CYP2C19 | |
| SCHEMBL30490080 | 0.84 | TYK2 (0.49) | TYK2BUB1JAK1CYP2C19 | |
| SCHEMBL24498505 | 0.81 | TYK2 (0.66) | TYK2JAK1CYP2C19 | |
| SCHEMBL29686730 | 0.81 | TYK2 (0.66) | TYK2JAK1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283954-A | Hydroxamate compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-116283954-A | Hydroxamate compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-06-23 | — | — | CN | disclosed |