Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 17/20 | 0.46 |
| ▸ | JAK1 | P23458 | 8/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | BUB1 | O43683 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30724634 | 0.93 | TYK2 (0.49) | TYK2JAK1CYP2C19KCNH2JAK2 | |
| SCHEMBL30490080 | 0.91 | TYK2 (0.49) | TYK2JAK1CYP2C19KCNH2BUB1 | |
| SCHEMBL30490067 | 0.87 | TYK2 (0.44) | TYK2JAK1CYP2C19BUB1 | |
| SCHEMBL30490252 | 0.85 | JAK2 (0.55) | TYK2JAK1KCNH2JAK2 | |
| SCHEMBL24497662 | 0.85 | TYK2 (0.47) | TYK2JAK1CYP2C19KCNH2JAK2 | |
| SCHEMBL29686586 | 0.85 | TYK2 (0.47) | TYK2JAK1CYP2C19KCNH2JAK2 | |
| SCHEMBL30490071 | 0.85 | TYK2 (0.51) | TYK2JAK1JAK2 | |
| SCHEMBL26524061 | 0.84 | TYK2 (0.50) | TYK2JAK1CYP2C19KCNH2JAK2 | |
| SCHEMBL29685368 | 0.84 | TYK2 (0.52) | TYK2JAK1CYP2C19KCNH2JAK2 | |
| SCHEMBL26117905 | 0.84 | TYK2 (0.52) | TYK2JAK1CYP2C19KCNH2JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283954-A | Hydroxamate compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-116283954-A | Hydroxamate compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-06-23 | — | — | CN | disclosed |