Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 8/20 | 0.48 |
| ▸ | JAK1 | P23458 | 3/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.39 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | LYN | P07948 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.39 |
| ▸ | SIK1 | P57059 | 1/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.39 |
| ▸ | SIK2 | Q9H0K1 | 1/20 | 0.39 |
| ▸ | SIK3 | Q9Y2K2 | 1/20 | 0.39 |
| ▸ | TTK | P33981 | 2/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | CCNC | P24863 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30490253 | 0.89 | TYK2 (0.47) | TYK2JAK1JAK2LRRK2CCNC | |
| SCHEMBL21013331 | 0.84 | TYK2 (0.48) | TYK2JAK1JAK2PRKAB2ABL1 | |
| SCHEMBL29686687 | 0.84 | TYK2 (0.48) | TYK2JAK1JAK2PRKAB2ABL1 | |
| SCHEMBL29686417 | 0.81 | JAK2 (0.64) | TYK2JAK1JAK2 | |
| SCHEMBL24497965 | 0.81 | JAK2 (0.64) | TYK2JAK1JAK2 | |
| SCHEMBL30490315 | 0.75 | TYK2 (0.52) | TYK2JAK1JAK2TGFBR1 | |
| SCHEMBL29685494 | 0.74 | TYK2 (0.37) | TYK2LRRK2TTKCCNCCDK8 | |
| SCHEMBL29686783 | 0.74 | TYK2 (0.47) | TYK2JAK1JAK2TTK | |
| SCHEMBL24498517 | 0.74 | TYK2 (0.47) | TYK2JAK1JAK2TTK | |
| SCHEMBL24498000 | 0.74 | TYK2 (0.50) | TYK2JAK1JAK2TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283954-A | Hydroxamate compound, preparation method and application thereof | 深圳微芯生物科技股份有限公司 | 2023-06-23 | — | — | CN | disclosed |