SCHEMBL30490253 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	TYK2	P29597	10/20	0.47

▸	JAK2	O60674	3/20	0.39

▸	LRRK2	Q5S007	2/20	0.38

▸	SLC22A12	Q96S37	1/20	0.38

▸	JAK1	P23458	4/20	0.37

▸	CCNC	P24863	1/20	0.37

▸	CDK8	P49336	1/20	0.37

▸	USP30	Q70CQ3	1/20	0.37

▸	IRAK4	Q9NWZ3	1/20	0.36

▸	IKBKE	Q14164	1/20	0.36

▸	TBK1	Q9UHD2	1/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30490300	0.89	TYK2 (0.48)	TYK2JAK2LRRK2JAK1CCNC
SCHEMBL29686783	0.85	TYK2 (0.47)	TYK2JAK2JAK1IRAK4
SCHEMBL24498517	0.85	TYK2 (0.47)	TYK2JAK2JAK1IRAK4
SCHEMBL30490252	0.83	JAK2 (0.55)	TYK2JAK2JAK1
SCHEMBL30724634	0.83	TYK2 (0.49)	TYK2JAK2JAK1
SCHEMBL29685327	0.81	JAK2 (0.62)	TYK2JAK2JAK1
SCHEMBL24498190	0.81	JAK2 (0.62)	TYK2JAK2JAK1
SCHEMBL30490071	0.81	TYK2 (0.51)	TYK2JAK2JAK1
SCHEMBL30490068	0.80	TYK2 (0.46)	TYK2JAK2JAK1
SCHEMBL30490080	0.80	TYK2 (0.49)	TYK2JAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-116283954-A	Hydroxamate compound, preparation method and application thereof	深圳微芯生物科技股份有限公司	2023-06-23	—	—	CN	disclosed