SCHEMBL304907

SCHEMBL304907

CCCC(Br)C(=O)OCC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ZDHHC7 Q9NXF8 1/20 0.48
ALDH1A1 P00352 3/20 0.42
TRPA1 O75762 1/20 0.41
LMNA P02545 1/20 0.40
HSD17B10 Q99714 1/20 0.40
POLB P06746 2/20 0.40
LCK P06239 1/20 0.39
PPARD Q03181 1/20 0.39
ZDHHC20 Q5W0Z9 1/20 0.39
ZDHHC2 Q9UIJ5 1/20 0.39
ALOX15 P16050 1/20 0.39
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
SOAT1 P35610 1/20 0.39
CHRM1 P11229 1/20 0.37
AKR1A1 P14550 1/20 0.37
CHRM3 P20309 1/20 0.37
HTR2A P28223 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1732719 1.00 ZDHHC7 (0.48) ZDHHC7ALDH1A1TRPA1LMNAHSD17B10
SCHEMBL1732564 1.00 ZDHHC7 (0.48) ZDHHC7ALDH1A1TRPA1LMNAHSD17B10
SCHEMBL36999 0.90 ZDHHC7 (0.47) ZDHHC7ALDH1A1TRPA1LMNAHSD17B10
SCHEMBL240521 0.90 ZDHHC7 (0.47) ZDHHC7ALDH1A1TRPA1LMNAHSD17B10
SCHEMBL729131 0.86 ZDHHC7 (0.60) ZDHHC7ALDH1A1TRPA1LMNAHSD17B10
SCHEMBL7353073 0.86 ZDHHC7 (0.60) ZDHHC7ALDH1A1TRPA1LMNAHSD17B10
SCHEMBL27836648 0.86 ZDHHC7 (0.60) ZDHHC7ALDH1A1TRPA1LMNAHSD17B10
SCHEMBL1415326 0.86 ZDHHC7 (0.59) ZDHHC7ALDH1A1TRPA1LMNAHSD17B10
SCHEMBL21811599 0.86 ZDHHC7 (0.48) ZDHHC7ALDH1A1TRPA1LCKPPARD
SCHEMBL1415641 0.86 ZDHHC7 (0.53) ZDHHC7ALDH1A1TRPA1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 474 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119342971-A ABX (ABX)3Metal halide perovskite film, preparation method and photovoltaic device 南京工业大学 2025-01-21 CN claimed
CN-116283648-B Substituted benzene acryloyl or benzene propionyl phenethylamine compound and preparation method and application thereof 中国医学科学院药用植物研究所 2024-03-19 CN claimed
CN-116283648-A Substituted benzene acryloyl or benzene propionyl phenethylamine compound and preparation method and application thereof 中国医学科学院药用植物研究所 2023-06-23 CN claimed
CN-111393332-B Alkyl-substituted ethyl acetate guanidine ionic liquid and preparation and application thereof 华东师范大学 2022-04-05 CN claimed
CN-111393332-A Alkyl-substituted ethyl acetate guanidine ionic liquid and preparation and application thereof 华东师范大学 2020-07-10 CN claimed
CN-103910741-A Bisbenzylisoquinoline betaine as well as preparation method thereof and application thereof in preparation of anti-tumor medicament UNIV SHANDONG NORMAL 2014-07-09 CN claimed
CN-103910738-A Bisbenzylisoquinoline quaternary ammonium salt as well as preparation method and application thereof in preparing antitumor drug UNIV SHANDONG NORMAL 2014-07-09 CN claimed
US-20260124191-A1 HISTONE DEACETYLASE INHIBITOR AND USES THEREOF NANJING HONGSHUN PHARMACEUTICAL TECHNOLOGY CO., LTD (CN) 2026-05-07 US disclosed
EP-4727916-A1 MIXED AMIDE ESTER CONTAINING LIPIDS FOR USE IN LIPID NANOPARTICLES Acuitas Therapeutics, Inc. (CA) 2026-04-22 EP disclosed
EP-4725940-A1 HISTONE DEACETYLASE INHIBITOR AND USE Nanjing Hongshun Pharmaceutical Technology Co., Ltd (CN) 2026-04-15 EP disclosed
US-20260078091-A1 Piperidinone Derivatives as MDM2 Inhibitors for the Treatment of Cancer AMGEN INC (US) 2026-03-19 US disclosed
EP-4559525-A2 INHIBITING HUMAN INTEGRIN ALPHA4BETA7 Morphic Therapeutic, Inc. (US) 2025-05-28 EP disclosed
CN-119968368-A Amide compound, preparation method, pharmaceutical composition and application thereof 中国科学院上海药物研究所 2025-05-09 CN disclosed
EP-0002278-A1 Ring-opened dimethylnorbornene and isopropylnorbornene copolymers The B.F. GOODRICH Company (US) 1979-06-13 EP disclosed
US-4148998-A ANTIBIOTICS YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 1979-04-10 US disclosed
US-4136247-A POLYALKENAMERS, IMPACT STRENGTH, HEAT RESISTANCE THE B. F. GOODRICH COMPANY (US) 1979-01-23 US disclosed
US-4136249-A POLYALKENAMERS, OXIDATION RESISTANCE, PROCESSABILITY THE B. F. GOODRICH COMPANY (US) 1979-01-23 US disclosed
US-4136248-A POLYALKENAMERS, GLASS TRANSITION TEMPERATURE THE B. F. GOODRICH COMPANY (US) 1979-01-23 US disclosed
US-4025708-A CATALYSTS THE B. F. GOODRICH COMPANY (US) 1977-05-24 US disclosed
US-3946019-A ANTHELMINTIC, MICROBIOCIDES, ANTIBILHARZIAL RHONE-POULENC, S.A. (FR) 1976-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078091-A1 Piperidinone Derivatives as MDM2 Inhibitors for the Treatment of Cancer TP53, HIF1AN, MDM2 ZDHHC7 2332/4885ALDH1A1 821/4885TRPA1 3165/4885
US-20260124191-A1 HISTONE DEACETYLASE INHIBITOR AND USES THEREOF HDAC1, HDAC3, HDAC2 ZDHHC7 110/4885ALDH1A1 2329/4885TRPA1 4443/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.