Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.37 |
| ▸ | DRD1 | P21728 | 3/20 | 0.37 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | HTR2C | P28335 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 3/20 | 0.37 |
| ▸ | HTR3A | P46098 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3044335 | 0.99 | HRH1 (0.37) | HRH1LMNACHRM2ADRA2ACHRM1 | |
| SCHEMBL3046843 | 0.90 | LMNA (0.38) | HRH1LMNACHRM2ADRA2ACHRM1 | |
| Hydrochloric Acid SCHEMBL3047924 | 0.89 | LMNA (0.38) | HRH1LMNACHRM2ADRA2ACHRM1 | |
| Hydrochloric Acid SCHEMBL3047738 | 0.81 | NPC1 (0.40) | HRH1LMNACHRM2ADRA2ACHRM1 | |
| SCHEMBL3047871 | 0.80 | MAPK1 (0.39) | HRH1LMNACHRM2ADRA2ACHRM1 | |
| Hydrochloric Acid SCHEMBL3042891 | 0.79 | DRD1 (0.38) | HRH1LMNACHRM2ADRA2ACHRM1 | |
| Hydrochloric Acid SCHEMBL14693626 | 0.79 | LMNA (0.38) | HRH1LMNACHRM2ADRA2ACHRM1 | |
| SCHEMBL3044376 | 0.78 | MAPK1 (0.40) | HRH1LMNACHRM2ADRA2ACHRM1 | |
| Hydrochloric Acid SCHEMBL3048000 | 0.75 | CHRM5 (0.37) | HRH1LMNACHRM2ADRA2ACHRM1 | |
| Hydrochloric Acid SCHEMBL3050393 | 0.75 | CHRM5 (0.37) | HRH1LMNACHRM2ADRA2ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2243778-B1 | PIPERIDINE DERIVATIVE | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 2014-10-29 | — | — | EP | disclosed |
| EP-2243778-A1 | PIPERIDINE DERIVATIVE | Nippon Zoki Pharmaceutical Co., Ltd. (JP) | 2010-10-27 | — | — | EP | disclosed |