Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHUK | O15111 | 16/20 | 1.00 |
| ▸ | ICOSLG | O75144 | 9/20 | 1.00 |
| ▸ | ICOS | Q9Y6W8 | 9/20 | 1.00 |
| ▸ | IKBKB | O14920 | 2/20 | 1.00 |
| ▸ | TYK2 | P29597 | 1/20 | 1.00 |
| ▸ | CLK1 | P49759 | 1/20 | 1.00 |
| ▸ | CLK2 | P49760 | 1/20 | 1.00 |
| ▸ | DYRK1A | Q13627 | 1/20 | 1.00 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 1.00 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.45 |
| ▸ | IKBKG | Q9Y6K9 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1420073 | 1.00 | CHUK (1.00) | CHUKICOSLGICOSIKBKBTYK2 | |
| SCHEMBL30039188 | 1.00 | CHUK (1.00) | CHUKICOSLGICOSIKBKBTYK2 | |
| SCHEMBL30342072 | 1.00 | CHUK (1.00) | CHUKICOSLGICOSIKBKBTYK2 | |
| Hydrochloric Acid SCHEMBL18114522 | 0.99 | CHUK (0.98) | CHUKICOSLGICOSIKBKBTYK2 | |
| SCHEMBL1798941 | 0.91 | CHUK (0.84) | CHUKICOSLGICOSIKBKBTYK2 | |
| SCHEMBL17225471 | 0.90 | CHUK (0.81) | CHUKICOSLGICOSIKBKBTYK2 | |
| SCHEMBL1801372 | 0.89 | ICOSLG (1.00) | CHUKICOSLGICOSIKBKBTYK2 | |
| SCHEMBL12653357 | 0.89 | CHUK (0.80) | CHUKICOSLGICOSIKBKBTYK2 | |
| SCHEMBL1797398 | 0.87 | CHUK (0.77) | CHUKICOSLGICOSIKBKBTYK2 | |
| SCHEMBL1803613 | 0.87 | CHUK (0.77) | CHUKICOSLGICOSIKBKBTYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4460301-A1 | SIGNALLING-PATHWAY INHIBITOR COMBINATIONS FOR USE IN THE TREATMENT OF CANCER DISEASES | Universität zu Köln (DE) | 2024-11-13 | — | — | EP | disclosed |
| WO-2023131576-A1 | SIGNALLING-PATHWAY INHIBITOR COMBINATIONS FOR USE IN THE TREATMENT OF CANCER DISEASES | UNIVERSITÄT ZU KÖLN (DE) | 2023-07-13 | — | — | WO | disclosed |