Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 12/20 | 0.41 |
| ▸ | TYMS | P04818 | 2/20 | 0.39 |
| ▸ | FPGS | Q05932 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25171471 | 1.00 | DHFR (0.41) | DHFRTYMSFPGS | |
| SCHEMBL25171470 | 1.00 | DHFR (0.41) | DHFRTYMSFPGS | |
| SCHEMBL25730745 | 0.93 | DHFR (0.35) | DHFRTYMSFPGS | |
| SCHEMBL30400917 | 0.93 | DHFR (0.35) | DHFRTYMSFPGS | |
| SCHEMBL24344222 | 0.92 | DHFR (0.41) | DHFRTYMSFPGS | |
| SCHEMBL25732353 | 0.89 | DHFR (0.43) | DHFRTYMSFPGS | |
| SCHEMBL24344220 | 0.86 | DHFR (0.35) | DHFRTYMSFPGS | |
| SCHEMBL24343805 | 0.84 | DHFR (0.41) | DHFRFPGS | |
| SCHEMBL25298807 | 0.84 | DHFR (0.41) | DHFRFPGS | |
| SCHEMBL25168419 | 0.83 | DHFR (0.33) | DHFRTYMSFPGS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4457229-A1 | ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES | Byondis B.V. (NL) | 2024-11-06 | — | — | EP | disclosed |
| WO-2023126297-A1 | ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES | BYONDIS B.V. (NL) | 2023-07-06 | — | — | WO | disclosed |