Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 5/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25296821 | 1.00 | DHFR (0.39) | DHFRNCOA3 | |
| SCHEMBL25168406 | 1.00 | DHFR (0.39) | DHFRNCOA3 | |
| SCHEMBL30492198 | 0.96 | DHFR (0.34) | DHFR | |
| SCHEMBL25730826 | 0.96 | DHFR (0.34) | DHFR | |
| SCHEMBL25730829 | 0.88 | KDM4E (0.32) | DHFR | |
| SCHEMBL25167002 | 0.87 | DHFR (0.38) | DHFRNCOA3 | |
| SCHEMBL30492196 | 0.87 | DHFR (0.38) | DHFRNCOA3 | |
| SCHEMBL25167003 | 0.87 | DHFR (0.38) | DHFRNCOA3 | |
| SCHEMBL30492189 | 0.84 | DHFR (0.49) | DHFR | |
| SCHEMBL25167232 | 0.84 | DHFR (0.49) | DHFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4457229-A1 | ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES | Byondis B.V. (NL) | 2024-11-06 | — | — | EP | disclosed |
| WO-2023126297-A1 | ANTIFOLATE LINKER-DRUGS AND ANTIBODY-DRUG CONJUGATES | BYONDIS B.V. (NL) | 2023-07-06 | — | — | WO | disclosed |