Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.65 |
| ▸ | NPC1 | O15118 | 8/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.65 |
| ▸ | LMNA | P02545 | 6/20 | 0.65 |
| ▸ | PKM | P14618 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 7/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | ECE2 | P0DPD6 | 2/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22501436 | 1.00 | RAB9A (0.65) | RAB9ANPC1KDM4ELMNAPKM | |
| SCHEMBL709663 | 0.93 | NPC1 (0.56) | RAB9ANPC1KDM4ELMNAPKM | |
| SCHEMBL709664 | 0.93 | NPC1 (0.56) | RAB9ANPC1KDM4ELMNAPKM | |
| SCHEMBL28443608 | 0.88 | RAB9A (0.80) | RAB9ANPC1KDM4ELMNAPKM | |
| SCHEMBL19084928 | 0.82 | RAB9A (0.57) | RAB9ANPC1KDM4ELMNAPKM | |
| SCHEMBL12068215 | 0.82 | KDM4E (0.57) | RAB9ANPC1KDM4ELMNAPKM | |
| SCHEMBL7555211 | 0.82 | KDM4E (0.57) | RAB9ANPC1KDM4ELMNAPKM | |
| SCHEMBL7555207 | 0.82 | KDM4E (0.57) | RAB9ANPC1KDM4ELMNAPKM | |
| Quinoline SCHEMBL28850584 | 0.81 | RAB9A (0.81) | RAB9ANPC1KDM4ELMNAPKM | |
| SCHEMBL9170780 | 0.80 | RAB9A (0.89) | RAB9ANPC1KDM4ELMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111494381-B | Application of alkenyl quinoline compound in preparation of antitumor drugs | 南方医科大学 | 2023-07-28 | — | — | CN | disclosed |