Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 1/20 | 0.48 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TGM2 | P21980 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29431191 | 0.88 | MDM2 (0.51) | TLR2TLR1MDM2PAX8TDP1 | |
| SCHEMBL13702142 | 0.88 | TLR2 (0.53) | TLR2TLR1ITGB3ITGA2BMDM2 | |
| SCHEMBL8259207 | 0.87 | PAX8 (0.50) | TLR2TLR1MDM2PAX8TDP1 | |
| SCHEMBL12340097 | 0.86 | KMT2A (0.48) | TLR2TLR1MDM2PAX8TDP1 | |
| SCHEMBL30193403 | 0.86 | MDM2 (0.52) | TLR2TLR1MDM2PAX8TDP1 | |
| SCHEMBL1755616 | 0.86 | PAX8 (0.55) | TLR2TLR1MDM2PAX8TDP1 | |
| SCHEMBL16870156 | 0.86 | MDM2 (0.52) | TLR2TLR1MDM2PAX8TDP1 | |
| SCHEMBL18421240 | 0.86 | MDM2 (0.52) | TLR2TLR1MDM2PAX8TDP1 | |
| SCHEMBL30193389 | 0.86 | MDM2 (0.52) | TLR2TLR1MDM2PAX8TDP1 | |
| SCHEMBL16870002 | 0.86 | MDM2 (0.52) | TLR2TLR1MDM2PAX8TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745413-B2 | Collection of traceable compounds and uses thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2010-06-29 | — | — | US | disclosed |
| US-20080176763-A1 | Collection of Traceable Compounds and Uses Thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2008-07-24 | — | — | US | disclosed |