⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6025089 | 1.00 | — | — | |
| SCHEMBL304953 | 1.00 | — | — | |
| SCHEMBL1112325 | 0.91 | — | — | |
| SCHEMBL387192 | 0.91 | — | — | |
| SCHEMBL387191 | 0.91 | — | — | |
| SCHEMBL3940295 | 0.88 | TSHR (0.48) | — | |
| SCHEMBL3326623 | 0.88 | TSHR (0.48) | — | |
| SCHEMBL383877 | 0.88 | TSHR (0.48) | — | |
| SCHEMBL384284 | 0.88 | TSHR (0.48) | — | |
| SCHEMBL3327144 | 0.88 | TSHR (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 375 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4146645-A1 | 3-AZABICYCLO(3.1.0)HEXANE DERIVATIVES HAVING KDM5 INHIBITORY ACTIVITY AND USE THEREOF | ONO Pharmaceutical Co., Ltd. (JP) | 2023-03-15 | — | — | EP | claimed |
| WO-2021223699-A1 | 3-AZABICYCLO(3.1.0)HEXANE DERIVATIVES HAVING KDM5 INHIBITORY ACTIVITY AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2021-11-11 | — | — | WO | claimed |
| US-20040171839-A1 | Polycyclic aryl and heteroaryl substituted 1, 4-quinones useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION | 2004-09-02 | — | — | US | claimed |
| US-20040006227-A1 | Polycyclic aryl and heteroaryl substituted 4-pyrones useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION | 2004-01-08 | — | — | US | claimed |
| US-20030236257-A1 | Polycyclic aryl and heteroaryl substituted 4-pyridones useful for selective inhibition of the cogulation cascade | PHARMACIA CORPORATION | 2003-12-25 | — | — | US | claimed |
| US-6660885-B2 | Serine protease inhibitor | PHARMACIA CORPORATION | 2003-12-09 | — | — | US | claimed |
| US-20030191306-A1 | Substituted N-Aliphatic-N-Aromatictertiary-Heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | G.D. SEARLE & CO. (US) | 2003-10-09 | — | — | US | claimed |
| US-20020032174-A1 | Polycyclic aryl and heteroaryl substituted 4-pyridones useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION | 2002-03-14 | — | — | US | claimed |
| US-20020025947-A1 | Polycyclic aryl and heteroaryl substituted benzenes useful for selective inhibition of the coagulation cascade | PHARMACIA CORPORATION | 2002-02-28 | — | — | US | claimed |
| US-20020022604-A1 | Polycyclic aryl and heteroaryl substituted 4-pyrones useful for selective inhibition of the coagulation cascade | PHAMACIA CORPORATION | 2002-02-21 | — | — | US | claimed |
| WO-2001087851-A1 | SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL PYRIMIDINONES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2001-11-22 | — | — | WO | claimed |
| WO-2001087842-A1 | SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL PYRIDONES USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2001-11-22 | — | — | WO | claimed |
| CN-114300745-B | Non-aqueous electrolyte, secondary battery and application of thiophosphamide as electrolyte additive | 惠州市豪鹏科技有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-118338888-A | Surfactant composition for cosmetic material and cosmetic material | 三洋化成工业株式会社 | 2024-07-12 | — | — | CN | disclosed |
| WO-2024128145-A1 | SUBSTITUTED POLYPHENYLENE SULFIDE RESIN | 株式会社ダイセル | 2024-06-20 | — | — | WO | disclosed |
| WO-2024127714-A1 | ZINC COMPLEX | 日触テクノファインケミカル株式会社 | 2024-06-20 | — | — | WO | disclosed |
| EP-0128028-A2 | Cephalosporin derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1984-12-12 | — | — | EP | disclosed |
| US-4431703-A | POLYSILOXANE AND SILOXANE LUBRICANTS; AMID DEVICES; TELEVISION; MAGNETIC TAPES | SONY CORPORATION (JP) | 1984-02-14 | — | — | US | disclosed |
| US-4369230-A | POLYSILOXANE LUBRICANTS | SONY CORPORATION (JP) | 1983-01-18 | — | — | US | disclosed |
| US-4207321-A | PROMOTES BLOOD PERFUSION | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-06-10 | — | — | US | disclosed |