SCHEMBL383877

SCHEMBL383877

C/[C]=C\CCCCCCC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.48
THRB P10828 1/20 0.44
FAAH O00519 2/20 0.42
TRPV1 Q8NER1 1/20 0.42
DNM1 Q05193 3/20 0.41
EP300 Q09472 1/20 0.38
GMNN O75496 1/20 0.37
USP2 O75604 1/20 0.37
LMNA P02545 1/20 0.37
CYP1A2 P05177 1/20 0.37
POLB P06746 1/20 0.37
MAPT P10636 1/20 0.37
CYP2C9 P11712 1/20 0.37
ALOX15 P16050 1/20 0.37
APEX1 P27695 1/20 0.37
CYP2C19 P33261 1/20 0.37
RECQL P46063 1/20 0.37
BLM P54132 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9202159 1.00
SCHEMBL384283 1.00 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL7573330 1.00 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL1419297 1.00
SCHEMBL3327144 1.00 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL3327147 1.00 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL3940295 1.00 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL3326623 1.00 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL384284 1.00 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1
SCHEMBL10320574 1.00 TSHR (0.48) TSHRTHRBFAAHTRPV1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8147931-B2 Cellulose-film modifier, cellulose composition, and optical cellulose film, polarizing plate-protecting film, polarizing plate, and liquid crystal display device, produced by using the same FUJIFILM CORPORATION (JP) 2012-04-03 US claimed
CN-118139909-A Beta-methyl-delta-valerolactone based polymer 株式会社可乐丽 2024-06-04 CN disclosed
CN-118139926-A Resin composition 株式会社可乐丽 2024-06-04 CN disclosed
WO-2023068345-A1 Β-METHYL-δ-VALEROLACTONE POLYMER 株式会社クラレ 2023-04-27 WO disclosed
WO-2023068348-A1 RESIN COMPOSITION 株式会社クラレ 2023-04-27 WO disclosed
WO-2023068346-A1 Β-METHYL-δ-VALEROLACTONE POLYMER 株式会社クラレ 2023-04-27 WO disclosed
CN-113321782-A Shoe press belt and method for producing shoe press belt 市川株式会社 2021-08-31 CN disclosed
CN-113322709-A Shoe press belt and method for producing shoe press belt 市川株式会社 2021-08-31 CN disclosed
CN-113322708-A Shoe press belt and method for producing shoe press belt 市川株式会社 2021-08-31 CN disclosed
US-20180353412-A1 COMPOSITIONS FOR DYEING KERATIN FIBERS L'OREAL (FR) 2018-12-13 US disclosed
WO-1992009561-A1 NEW AMIDE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1992-06-11 WO disclosed
EP-0003883-B1 AMINO-DIBENZOPYRANS, THEIR PREPARATION, FORMULATIONS CONTAINING THEM AND THEIR USE AS PHARMACEUTICALS ELI LILLY AND COMPANY (US) 1982-10-06 EP disclosed
EP-0004753-B1 PREPARATION OF TETRAHYDROBENZOXOCINS AND CIS-HEXAHYDRODIBENZOPYRANONES ELI LILLY AND COMPANY (US) 1982-05-26 EP disclosed
EP-0004172-B1 BENZOCYCLOHEPTAPYRANS, THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THEM ELI LILLY AND COMPANY (US) 1982-04-07 EP disclosed
US-4195024-A HYPOTENSIVE AGENTS ELI LILLY AND COMPANY (US) 1980-03-25 US disclosed
US-4195025-A 9-Amino-dibenzopyrans ELI LILLY AND COMPANY (US) 1980-03-25 US disclosed
EP-0004172-A1 Benzocycloheptapyrans, their preparation and pharmaceutical formulations containing them ELI LILLY AND COMPANY (US) 1979-09-19 EP disclosed
US-4152450-A 9-Amino-dibenzopyrans ELI LILLY AND COMPANY (US) 1979-05-01 US disclosed
US-4152451-A HYPOTENSIVE AGENTS ELI LILLY AND COMPANY (US) 1979-05-01 US disclosed
US-4131614-A Process for preparing cis-hexahydrodibenzopyranones ELI LILLY AND COMPANY (US) 1978-12-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180353412-A1 COMPOSITIONS FOR DYEING KERATIN FIBERS KRT18, CUTA, DSG1 TSHR 4502/4885THRB 3806/4885FAAH 2767/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.