Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 19/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 14/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 11/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 13/20 | 0.52 |
| ▸ | PLK4 | O00444 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.50 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.50 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.50 |
| ▸ | CSNK1G3 | Q9Y6M4 | 1/20 | 0.50 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL796431 | 1.00 | ADORA2B (0.58) | ADORA2BADORA2AADORA3ADORA1PLK4 | |
| SCHEMBL1546106 | 0.90 | ADORA2B (0.58) | ADORA2BADORA2AADORA3ADORA1PLK4 | |
| SCHEMBL1546641 | 0.89 | ADORA2B (0.56) | ADORA2BADORA2AADORA3ADORA1SCD5 | |
| SCHEMBL8979404 | 0.88 | ADORA2B (0.49) | ADORA2BADORA2AADORA3ADORA1 | |
| SCHEMBL1546614 | 0.87 | ADORA2B (0.59) | ADORA2BADORA2AADORA3ADORA1SCD5 | |
| SCHEMBL5541331 | 0.87 | ADORA2B (0.45) | ADORA2BADORA2AADORA3ADORA1PLK4 | |
| SCHEMBL1723697 | 0.87 | ADORA2B (0.52) | ADORA2BADORA2AADORA3ADORA1RPS6KA3 | |
| SCHEMBL1546107 | 0.87 | ADORA2B (0.54) | ADORA2BADORA2AADORA3ADORA1PLK4 | |
| SCHEMBL244147 | 0.86 | ADORA2B (0.55) | ADORA2BADORA2AADORA3ADORA1PLK4 | |
| SCHEMBL1546781 | 0.85 | KLKB1 (0.52) | ADORA2BADORA2AADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111770926-B | Tricyclic compounds, compositions and pharmaceutical uses thereof | 因佩蒂斯生物科学有限公司 | 2023-07-21 | — | — | CN | disclosed |