Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.52 |
| ▸ | BPTF | Q12830 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 2/20 | 0.38 |
| ▸ | FPR1 | P21462 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23067588 | 1.00 | DPP4 (0.52) | DPP4BPTFDHFROPRL1OPRM1 | |
| SCHEMBL21121423 | 0.80 | DPP4 (0.46) | DPP4BPTFDHFROPRL1OPRM1 | |
| SCHEMBL24591550 | 0.80 | DPP4 (0.46) | DPP4BPTFDHFROPRL1OPRM1 | |
| SCHEMBL21580294 | 0.80 | DPP4 (0.54) | DPP4BPTFDHFROPRL1OPRM1 | |
| SCHEMBL23067586 | 0.80 | CA12 (0.57) | DPP4 | |
| SCHEMBL21580330 | 0.77 | DPP4 (0.47) | DPP4CHRM4CHRM2 | |
| SCHEMBL25391324 | 0.76 | CYP3A4 (0.49) | DHFRUSP30FPR2FPR1CHRM4 | |
| SCHEMBL31615602 | 0.76 | CYP3A4 (0.49) | DHFRUSP30FPR2FPR1CHRM4 | |
| SCHEMBL21121417 | 0.76 | ALDH1A1 (0.52) | DPP4 | |
| SCHEMBL1009572 | 0.75 | BPTF (0.51) | DPP4BPTFBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111770926-B | Tricyclic compounds, compositions and pharmaceutical uses thereof | 因佩蒂斯生物科学有限公司 | 2023-07-21 | — | — | CN | disclosed |