SCHEMBL30495616

C[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O)[C@@H](C)O

nearest known ligand 0.52

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	17/20	0.52

▸	SCTR	P47872	1/20	0.52

▸	VIPR1	P32241	2/20	0.49

▸	VIPR2	P41587	1/20	0.47

▸	GCGR	P47871	1/20	0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30997433	0.90	GLP1R (0.43)	GLP1RSCTRVIPR1GCGR
SCHEMBL30432968	0.89	VIPR1 (0.59)	GLP1RVIPR1VIPR2
SCHEMBL31182488	0.88	GLP1R (0.48)	GLP1RSCTRVIPR1VIPR2GCGR
SCHEMBL31410841	0.88	BACE1 (0.45)	GLP1RSCTR
SCHEMBL30648465	0.88	GLP1R (0.47)	GLP1RVIPR1VIPR2
SCHEMBL31000898	0.87	GLP1R (0.61)	GLP1RSCTRVIPR1VIPR2
SCHEMBL30956347	0.87	GLP1R (0.51)	GLP1RSCTRVIPR1VIPR2GCGR
SCHEMBL30956345	0.87	GLP1R (0.51)	GLP1RSCTRGCGR
SCHEMBL30262026	0.87	VIPR2 (0.51)	GLP1RSCTRVIPR1VIPR2GCGR
SCHEMBL29519822	0.86	GLP1R (0.52)	GLP1RSCTRVIPR1VIPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20230190887-A1	TARGETING G3BP AGGREGATION TO PREVENT NEURODEGENERATION	UNIVERSITY OF SOUTH CAROLINA (US)	2023-06-22	—	—	US	disclosed