SCHEMBL30648465

CC[C@H](C)[C@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@@H](N)CCCNC(=N)N)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	14/20	0.47

▸	BACE1	P56817	2/20	0.46

▸	VIPR1	P32241	2/20	0.46

▸	KEAP1	Q14145	1/20	0.46

▸	VIPR2	P41587	2/20	0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30887565	0.90	KISS1R (0.51)	GLP1RBACE1VIPR1VIPR2
SCHEMBL30432968	0.89	VIPR1 (0.59)	GLP1RVIPR1VIPR2
SCHEMBL29822692	0.88	GLP1R (0.59)	GLP1RKEAP1
SCHEMBL30495616	0.88	GLP1R (0.52)	GLP1RVIPR1VIPR2
SCHEMBL14921120	0.87	VIPR2 (0.44)	GLP1RVIPR1VIPR2
SCHEMBL30257845	0.87	GLP1R (0.53)	GLP1RKEAP1
SCHEMBL31031499	0.87	GLP1R (0.57)	GLP1RKEAP1
SCHEMBL30368368	0.86	GLP1R (0.42)	GLP1RBACE1VIPR1VIPR2
SCHEMBL30811634	0.86	GLP1R (0.45)	GLP1RVIPR1KEAP1
SCHEMBL29767364	0.86	GLP1R (0.50)	GLP1RVIPR1VIPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-116948034-B	Active type heterophagy antibody blocker Block-5S and preparation method thereof	南京珀尔泰生物技术有限公司	2024-06-25	—	—	CN	disclosed
CN-116948034-A	Active type heterophagy antibody blocker Block-5S and preparation method thereof	南京珀尔泰生物技术有限公司	2023-10-27	—	—	CN	disclosed