Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.78 |
| ▸ | TP53 | P04637 | 1/20 | 0.78 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.72 |
| ▸ | SLC29A1 | Q99808 | 6/20 | 0.71 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.71 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.71 |
| ▸ | NT5E | P21589 | 2/20 | 0.68 |
| ▸ | PGK1 | P00558 | 1/20 | 0.68 |
| ▸ | PGK2 | P07205 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.64 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7100664 | 1.00 | LMNA (0.78) | LMNATP53CYP2C19SLC29A1ADORA3 | |
| SCHEMBL637421 | 1.00 | LMNA (0.78) | LMNATP53CYP2C19SLC29A1ADORA3 | |
| SCHEMBL12987511 | 1.00 | LMNA (0.78) | LMNATP53CYP2C19SLC29A1ADORA3 | |
| SCHEMBL637420 | 1.00 | LMNA (0.78) | LMNATP53CYP2C19SLC29A1ADORA3 | |
| SCHEMBL18464460 | 1.00 | LMNA (0.78) | LMNATP53CYP2C19SLC29A1ADORA3 | |
| SCHEMBL23680013 | 1.00 | LMNA (0.78) | LMNATP53CYP2C19SLC29A1ADORA3 | |
| SCHEMBL14163069 | 1.00 | LMNA (0.78) | LMNATP53CYP2C19SLC29A1ADORA3 | |
| SCHEMBL14928763 | 1.00 | LMNA (0.78) | LMNATP53CYP2C19SLC29A1ADORA3 | |
| SCHEMBL14853642 | 1.00 | LMNA (0.78) | LMNATP53CYP2C19SLC29A1ADORA3 | |
| SCHEMBL18844791 | 1.00 | LMNA (0.78) | LMNATP53CYP2C19SLC29A1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111902420-B | Cyclic dinucleotides as anticancer agents | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-111344297-B | Cyclic dinucleotides as anticancer agents | 百时美施贵宝公司 | 2023-10-20 | — | — | CN | disclosed |
| WO-2023152709-A1 | RNA POLYMERASE INHIBITORS AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2023-08-17 | — | — | WO | disclosed |