Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 14/20 | 0.41 |
| ▸ | HTR2C | P28335 | 13/20 | 0.41 |
| ▸ | HTR2A | P28223 | 12/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30496984 | 0.86 | PARP1 (0.45) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL30496977 | 0.77 | PARP1 (0.45) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL30459786 | 0.77 | PARP1 (0.43) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL30936963 | 0.75 | PARP1 (0.45) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL30698072 | 0.75 | HTR2B (0.62) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL30376302 | 0.75 | HTR2B (0.62) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL660471 | 0.75 | HTR2B (0.62) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL2333387 | 0.74 | HTR2B (0.49) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL30459956 | 0.74 | HTR2B (0.50) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| Hydrochloric Acid SCHEMBL28593152 | 0.74 | HTR2B (0.60) | PARP1HTR2BHTR2CHTR2AHTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116457344-A | Low molecular weight protein degradation agent and application thereof | 凯普托尔治疗学股份有限公司 | 2023-07-18 | — | — | CN | disclosed |