Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 16/20 | 0.38 |
| ▸ | HTR2C | P28335 | 15/20 | 0.38 |
| ▸ | HTR2A | P28223 | 12/20 | 0.38 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30496984 | 0.89 | PARP1 (0.45) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL30720892 | 0.82 | PARP1 (0.42) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL30351685 | 0.80 | PARP1 (0.40) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL30351684 | 0.79 | PARP1 (0.40) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL30004312 | 0.78 | PARP1 (0.41) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL27093617 | 0.78 | PARP1 (0.41) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL30936963 | 0.78 | PARP1 (0.45) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL30496983 | 0.77 | PARP1 (0.43) | PARP1HTR2BHTR2CHTR2AHTR3E | |
| SCHEMBL25229173 | 0.77 | MAPK1 (0.35) | MAPK1 | |
| SCHEMBL30352049 | 0.76 | PARP1 (0.38) | PARP1HTR2BHTR2CHTR2AHTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | disclosed |