SCHEMBL30496995

SCHEMBL30496995

CC1c2cc(CN)ccc2C(=O)N1C1CCC(=O)NC1=O

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 19/20 0.46
▸ DDB1 Q16531 12/20 0.46
▸ ALDH1A1 P00352 1/20 0.43
▸ CHRM2 P08172 1/20 0.43
▸ OPRM1 P35372 1/20 0.43
▸ IKZF3 Q9UKT9 1/20 0.43
▸ CYP1A2 P05177 1/20 0.43
▸ TSHR P16473 1/20 0.43
▸ TDP1 Q9NUW8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25246941 1.00 CRBN (0.46) CRBNDDB1ALDH1A1CHRM2OPRM1
SCHEMBL27267015 0.83 CRBN (0.47) CRBNDDB1ALDH1A1CHRM2OPRM1
SCHEMBL30930626 0.83 CRBN (0.47) CRBNDDB1ALDH1A1CHRM2OPRM1
SCHEMBL17697796 0.83 CRBN (0.42) CRBNDDB1ALDH1A1CHRM2OPRM1
SCHEMBL26103591 0.82 CRBN (0.60) CRBNDDB1ALDH1A1CHRM2OPRM1
SCHEMBL23565110 0.80 CRBN (0.44) CRBNDDB1ALDH1A1CHRM2OPRM1
SCHEMBL31739101 0.80 CRBN (0.46) CRBNDDB1ALDH1A1CHRM2OPRM1
SCHEMBL19771065 0.79 CRBN (0.61) CRBNDDB1ALDH1A1CHRM2OPRM1
SCHEMBL25213150 0.79 CRBN (0.54) CRBNDDB1IKZF3
SCHEMBL31736587 0.78 IKZF2 (0.42) CRBNDDB1ALDH1A1CHRM2OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116457344-B Low molecular weight protein degradation agent and application thereof 凯普托尔治疗学股份有限公司 2026-05-12 — — CN disclosed
CN-116457344-A Low molecular weight protein degradation agent and application thereof 凯普托尔治疗学股份有限公司 2023-07-18 — — CN disclosed
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