SCHEMBL304974

SCHEMBL304974

CCCCCCCc1ccc(O)c(C=O)c1

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 1/20 0.84
KAT8 Q9H7Z6 2/20 0.59
PPARA Q07869 1/20 0.55
ESR1 P03372 2/20 0.51
ADRA2A P08913 2/20 0.51
ADORA3 P0DMS8 2/20 0.51
TACR2 P21452 2/20 0.51
SLC6A2 P23975 2/20 0.51
SLC6A4 P31645 2/20 0.51
SLC6A3 Q01959 2/20 0.51
KDM4E B2RXH2 1/20 0.51
ALDH1A1 P00352 1/20 0.51
LMNA P02545 1/20 0.51
SHBG P04278 1/20 0.51
TP53 P04637 1/20 0.51
CYP3A4 P08684 1/20 0.51
HSPD1 P10809 1/20 0.51
ADRB3 P13945 1/20 0.51
HTR2C P28335 1/20 0.51
HSPE1 P61604 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9318508 1.00 CDK1 (0.84) CDK1KAT8PPARAESR1ADRA2A
SCHEMBL11415237 1.00 CDK1 (0.84) CDK1KAT8PPARAESR1ADRA2A
SCHEMBL27840244 1.00 CDK1 (0.84) CDK1KAT8PPARAESR1ADRA2A
SCHEMBL304629 1.00 CDK1 (0.84) CDK1KAT8PPARAESR1ADRA2A
SCHEMBL304650 1.00 CDK1 (0.84) CDK1KAT8PPARAESR1ADRA2A
SCHEMBL305081 1.00 CDK1 (0.84) CDK1KAT8PPARAESR1ADRA2A
SCHEMBL11421416 1.00 CDK1 (0.84) CDK1KAT8PPARAESR1ADRA2A
SCHEMBL6882282 1.00 CDK1 (0.84) CDK1KAT8PPARAESR1ADRA2A
SCHEMBL27994247 0.98 CDK1 (0.81) CDK1KAT8PPARAESR1ADRA2A
SCHEMBL305077 0.98 CDK1 (0.81) CDK1KAT8PPARAESR1ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0721482-B1 ADHESION PROMOTER FOR PVC COMPOUNDS DU PONT (US) 1997-11-05 EP claimed
US-5219954-A Improved ductility, flexural stiffness, modulus and tensile strength SHELL OIL COMPANY (US) 1993-06-15 US claimed
US-8093161-B2 A melt spinning synthetic multicomponent fibers having a shell-core polymers, high degree of recoverable elongation, crimped stretch fibers Invista North America S.àr.l. (US) 2012-01-10 US disclosed
EP-1430170-B1 STRETCHABLE NONWOVEN WEB AND METHOD THEREFOR INVISTA TECH SARL (CH) 2008-07-02 EP disclosed
EP-1322802-B1 STRETCHABLE FIBERS OF POLYMERS, SPINNERETS USEFUL TO FORM THE FIBERS, AND ARTICLES PRODUCED THEREFROM INVISTA TECH SARL (US) 2005-08-24 EP disclosed
EP-1320638-B1 STRETCHABLE POLYMERIC FIBERS AND ARTICLES PRODUCED THEREFROM INVISTA TECH SARL (US) 2005-06-15 EP disclosed
US-20050008855-A1 Hetero-composite yarn, fabrics thereof and methods of making INVISTA SARL (US) 2005-01-13 US disclosed
US-6783853-B2 SELF- BULKING, TEXTILE YARN WITH HIGH STRETCH RECOVERY, PRODUCED FROM HIGH-SHRINKAGE, LATENT STRETCH, MELT SPUN BICONSTITUENT FIBER AND ONE OR MORE LOWER SHRINKAGE FIBERS; FOR USE IN GARMENTS INVISTA NORTH AMERICA S.A.R.L. 2004-08-31 US disclosed
EP-1432856-A1 HETERO-COMPOSITE YARN, FABRICS THEREOF AND METHODS OF MAKING INVISTA Technologies S.à.r.l. (US) 2004-06-30 EP disclosed
EP-1430170-A1 STRETCHABLE NONWOVEN WEB AND METHOD THEREFOR E. I. du Pont de Nemours and Company (US) 2004-06-23 EP disclosed
US-20030186051-A1 Self- bulking, textile yarn with high stretch recovery, produced from high-shrinkage, latent stretch, melt spun biconstituent fiber and one or more lower shrinkage fibers; for use in garments INVISTA NORTH AMERICA S.A.R.L. 2003-10-02 US disclosed
WO-2002027083-A1 STRETCHABLE POLYMERIC FIBERS AND ARTICLES PRODUCED THEREFROM E. I. DU PONT DE NEMOURS AND COMPANY (US) 2002-04-04 WO disclosed
WO-2002027082-A1 STRETCHABLE FIBERS OF POLYMERS, SPINNERETS USEFUL TO FORM THE FIBERS, AND ARTICLES PRODUCED THEREFROM E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-04-04 WO disclosed
CN-1035813-C Chemical process ZENECA LTD (GB) 1997-09-10 CN disclosed
EP-0530904-B1 A composition comprising a polymer of carbon monoxide and ethylenically unsaturated compounds SHELL INT RESEARCH (NL) 1997-03-05 EP disclosed
EP-0529870-B1 Preparation of 2-hydroxyarylaldehydes ZENECA LTD (GB) 1996-01-17 EP disclosed
US-5260487-A Process for the preparation of 2-hydroxyarylaldehydes IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-11-09 US disclosed
CN-1073934-A Novel method for synthesizing 2-hydroxy aromatic aldehyde compound ICI PLC (GB) 1993-07-07 CN disclosed
EP-0530904-A1 A composition comprising a polymer of carbon monoxide and ethylenically unsaturated compounds SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1993-03-10 EP disclosed
EP-0529870-A2 Preparation of 2-hydroxyarylaldehydes ZENECA LIMITED (GB) 1993-03-03 EP disclosed