Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.81 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.56 |
| ▸ | PPARA | Q07869 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 2/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | TACR2 | P21452 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SHBG | P04278 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL304629 | 0.98 | CDK1 (0.84) | CDK1KAT8PPARAESR1ADRA2A | |
| SCHEMBL304974 | 0.98 | CDK1 (0.84) | CDK1KAT8PPARAESR1ADRA2A | |
| SCHEMBL6882282 | 0.98 | CDK1 (0.84) | CDK1KAT8PPARAESR1ADRA2A | |
| SCHEMBL27840244 | 0.98 | CDK1 (0.84) | CDK1KAT8PPARAESR1ADRA2A | |
| SCHEMBL304650 | 0.98 | CDK1 (0.84) | CDK1KAT8PPARAESR1ADRA2A | |
| SCHEMBL9318508 | 0.98 | CDK1 (0.84) | CDK1KAT8PPARAESR1ADRA2A | |
| SCHEMBL305081 | 0.98 | CDK1 (0.84) | CDK1KAT8PPARAESR1ADRA2A | |
| SCHEMBL11415237 | 0.98 | CDK1 (0.84) | CDK1KAT8PPARAESR1ADRA2A | |
| SCHEMBL11421416 | 0.98 | CDK1 (0.84) | CDK1KAT8PPARAESR1ADRA2A | |
| SCHEMBL19497893 | 0.97 | CDK1 (0.76) | CDK1KAT8PPARAESR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4587669-B2 | — | — | 2010-11-24 | — | — | JP | claimed |
| JP-2005509662-A | — | — | 2005-04-14 | — | — | JP | claimed |
| EP-1443915-A1 | PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING OXY GROUP-BEARING AROMATIC ALDEHYDES | Cutanix Corporation (US) | 2004-08-11 | — | — | EP | claimed |
| US-20030157154-A1 | Compositions containing hydroxy aromatic aldehydes and their use in treatments | CUTANIX CORPORATION | 2003-08-21 | — | — | US | claimed |
| WO-2003043621-A1 | PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING OXY GROUP-BEARING AROMATIC ALDEHYDES | CUTANIX CORPORATION (US) | 2003-05-30 | — | — | WO | claimed |
| EP-0721482-B1 | ADHESION PROMOTER FOR PVC COMPOUNDS | DU PONT (US) | 1997-11-05 | — | — | EP | claimed |
| US-5219954-A | Improved ductility, flexural stiffness, modulus and tensile strength | SHELL OIL COMPANY (US) | 1993-06-15 | — | — | US | claimed |
| US-20230257655-A1 | COMPOUND WITH VERTICAL ALIGNMENT, LIQUID CRYSTAL DISPLAY PANEL, AND PREPARATION METHOD THEREOF | TCL CHINA STAR OPTOELECTRONICS TECHNOLOGY CO., LTD. (CN) | 2023-08-17 | — | — | US | disclosed |
| US-10723952-B2 | Polymerizable compound and optically anisotropic body | DIC CORPORATION (JP) | 2020-07-28 | — | — | US | disclosed |
| US-9981901-B2 | IRE-1α inhibitors | FOSUN ORINOVE PHARMATECH, INC. (CN) | 2018-05-29 | — | — | US | disclosed |
| US-20170306233-A1 | POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY | DIC CORPORATION (JP) | 2017-10-26 | — | — | US | disclosed |
| US-20170306233-A1 | POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY | DIC CORPORATION (JP) | 2017-10-26 | — | — | US | disclosed |
| US-20170152206-A1 | IRE-1alpha INHIBITORS | FOSUN ORINOVE PHARMATECH, INC. (CN) | 2017-06-01 | — | — | US | disclosed |
| US-20020106509-A1 | Stretchable fibers of polymers, spinnerets useful to form the fibers, and articles produced therefrom | INVISTA NORTH AMERICA S.A.R.L. | 2002-08-08 | — | — | US | disclosed |
| WO-2002027082-A1 | STRETCHABLE FIBERS OF POLYMERS, SPINNERETS USEFUL TO FORM THE FIBERS, AND ARTICLES PRODUCED THEREFROM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-04-04 | — | — | WO | disclosed |
| WO-2002027083-A1 | STRETCHABLE POLYMERIC FIBERS AND ARTICLES PRODUCED THEREFROM | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-04-04 | — | — | WO | disclosed |
| EP-0530904-B1 | A composition comprising a polymer of carbon monoxide and ethylenically unsaturated compounds | SHELL INT RESEARCH (NL) | 1997-03-05 | — | — | EP | disclosed |
| US-5219954-A | Improved ductility, flexural stiffness, modulus and tensile strength | SHELL OIL COMPANY (US) | 1993-06-15 | — | — | US | disclosed |
| EP-0530904-A1 | A composition comprising a polymer of carbon monoxide and ethylenically unsaturated compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-03-10 | — | — | EP | disclosed |
| US-5166266-A | Terpolymer of carbon monoxide, ethylene, and unsaturated hydrocarbon monomer; vapor barriers | SHELL OIL COMPANY (US) | 1992-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030157154-A1 | Compositions containing hydroxy aromatic aldehydes and their use in treatments | TYR, HRH1, HRH2 | CDK1 4235/4885KAT8 832/4885PPARA 116/4885 |
| US-20170152206-A1 | IRE-1alpha INHIBITORS | XBP1, DDIT3, ERN1 | CDK1 1895/4885KAT8 4101/4885PPARA 3980/4885 |
| US-20170306233-A1 | POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY | SMC4, PHOSPHO1, SMCHD1 | CDK1 750/4885KAT8 2979/4885PPARA 2834/4885 |
| US-10723952-B2 | Polymerizable compound and optically anisotropic body | SMC4, SMCHD1, PHOSPHO1 | CDK1 708/4885KAT8 2988/4885PPARA 2894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.