Psyle A

SCHEMBL30497730

CC[C@H](C)[C@@H]1NC(=O)CNC(=O)[C@@H](CC(N)=O)NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H]2CSSC[C@@H]3NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc4ccccc4)NC(=O)[C@H](C(C)C)NC(=O)[C@H]4CSSC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](C)NC1=O)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)N4)NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](Cc1ccccc1)NC3=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N2

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

	gene	UniProt	supporting neighbours	confidence
▸	ELANE	P08246	4/20	0.72

▸	ST14	Q9Y5Y6	1/20	0.59

▸	PLG	P00747	1/20	0.58

▸	TFPI	P10646	4/20	0.56

▸	ITGB3	P05106	1/20	0.55

▸	ITGB1	P05556	1/20	0.55

▸	ITGAV	P06756	1/20	0.55

▸	ITGA5	P08648	1/20	0.55

▸	ITGB5	P18084	1/20	0.55

▸	NECTIN4	Q96NY8	3/20	0.54

▸	SLC6A3	Q01959	1/20	0.54

▸	MC4R	P32245	1/20	0.53

▸	MC1R	Q01726	1/20	0.53

▸	CTNNB1	P35222	1/20	0.51

▸	FURIN	P09958	1/20	0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Cycloviolacin O14 SCHEMBL30831407	0.94	ELANE (0.67)	ELANEST14PLGTFPIITGB3
Cycloviolin C SCHEMBL30831410	0.93	ELANE (0.75)	ELANEST14TFPIITGB3ITGB1
Cycloviolacin O15 SCHEMBL30831403	0.92	ELANE (0.68)	ELANEST14PLGTFPIITGB3
Cycloviolin D SCHEMBL30831405	0.92	ELANE (0.75)	ELANEST14PLGTFPIITGB3
Circulin B SCHEMBL29508758	0.91	ELANE (0.74)	ELANEST14PLGTFPIITGB3
Palicourein SCHEMBL30178312	0.91	ELANE (0.76)	ELANEST14TFPIITGB3ITGB1
Cycloviolin B SCHEMBL30831402	0.91	ELANE (0.67)	ELANEST14PLGTFPIITGB3
Circulin C SCHEMBL29508755	0.91	ELANE (0.73)	ELANEST14PLGTFPIITGB3
Circulin A SCHEMBL29508768	0.90	ELANE (0.73)	ELANETFPIITGB3ITGB1ITGAV
Cyclopsychotride A SCHEMBL30116118	0.88	ELANE (0.61)	ELANEST14PLGTFPIITGB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-11723932-B2	Microorganisms programmed to produce immune modulators and anti-cancer therapeutics in tumor cells	SYNLOGIC OPERATING COMPANY, INC. (US)	2023-08-15	—	—	US	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-11723932-B2	Microorganisms programmed to produce immune modulators and anti-cancer therapeutics in tumor cells	PDCD1, CD274, PDCD4	ELANE 3715/4885ST14 1038/4885PLG 815/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.