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Sugi Predict / Compounds / Cyclopsychotride A

Cyclopsychotride A

Cyclopsychotride A

SCHEMBL30116118

CC[C@H](C)[C@@H]1NC(=O)[C@H]2CCCN2C(=O)[C@@H](CS)NC(=O)CNC(=O)[C@@H](CCC(=O)O)NC(=O)[C@@H](CO)NC(=O)[C@@H](CS)NC(=O)[C@@H](C(C)C)NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H]2CCCN2C(=O)[C@@H](CS)NC(=O)[C@H]([C@H](C)O)NC(=O)[C@@H](C(C)C)NC(=O)[C@H]([C@H](C)O)NC(=O)[C@@H](C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)CNC(=O)[C@@H](CS)NC(=O)[C@@H](CO)NC(=O)[C@@H](CS)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CO)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](C(C)C)NC(=O)[C@@H](CS)NC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](CC(N)=O)NC(=O)[C@@H](CO)NC1=O

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 4/20 0.61
▸ TFPI P10646 4/20 0.60
▸ ST14 Q9Y5Y6 1/20 0.59
▸ ITGB3 P05106 1/20 0.55
▸ ITGB1 P05556 1/20 0.55
▸ ITGAV P06756 1/20 0.55
▸ ITGA5 P08648 1/20 0.55
▸ ITGB5 P18084 1/20 0.55
▸ SLC6A3 Q01959 1/20 0.52
▸ PLG P00747 1/20 0.52
▸ NECTIN4 Q96NY8 1/20 0.52
▸ PCSK9 Q8NBP7 1/20 0.51
▸ EPHA2 P29317 2/20 0.51
▸ MC4R P32245 1/20 0.50
▸ MC1R Q01726 1/20 0.50
▸ KEAP1 Q14145 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Psyle A SCHEMBL30497730 0.88 ELANE (0.72) ELANETFPIST14ITGB3ITGB1
Cycloviolacin O14 SCHEMBL30831407 0.87 ELANE (0.67) ELANETFPIST14ITGB3ITGB1
Cycloviolacin O15 SCHEMBL30831403 0.87 ELANE (0.68) ELANETFPIST14ITGB3ITGB1
Cycloviolin B SCHEMBL30831402 0.87 ELANE (0.67) ELANETFPIST14ITGB3ITGB1
Palicourein SCHEMBL30178312 0.87 ELANE (0.76) ELANETFPIST14ITGB3ITGB1
Cycloviolin C SCHEMBL30831410 0.86 ELANE (0.75) ELANETFPIST14ITGB3ITGB1
Circulin B SCHEMBL29508758 0.85 ELANE (0.74) ELANETFPIST14ITGB3ITGB1
Circulin C SCHEMBL29508755 0.85 ELANE (0.73) ELANETFPIST14ITGB3ITGB1
SCHEMBL17133082 0.83 FLT1 (0.57) ELANETFPIITGB3ITGB1ITGAV
Tyrocidine A1 SCHEMBL31412201 0.82 HDAC4 (0.56) ELANETFPIITGB3ITGB1ITGAV

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4164693-A1 NANOLIPOPROTEIN-POLYPEPTIDE CONJUGATES AND COMPOSITIONS, SYSTEMS, AND METHODS USING SAME Genentech, Inc. (US) 2023-04-19 — — EP claimed
CN-115803063-A Nanolipid protein-polypeptide conjugates and compositions, systems, and methods of use thereof 基因泰克公司 2023-03-14 — — CN claimed
US-20250290084-A1 CONTROL OF PHENOTYPE IN PLANTS KENDRED, LLC 2025-09-18 — — US disclosed
US-12344852-B2 Control of phenotype in plants GREENVENUS, LLC (US) 2025-07-01 — — US disclosed
US-20240092846-A1 ENGINEERED CYCLOTIDES WITH POTENT BROAD ANTIMICROBIAL ACTIVITY NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2024-03-21 — — US disclosed
US-20240059755-A1 NANOLIPOPROTEIN-POLYPEPTIDE CONJUGATES AND COMPOSITIONS, SYSTEMS, AND METHODS USING SAME GENENTECH, INC (US) 2024-02-22 — — US disclosed
US-20230130408-A1 CONTROL OF PHENOTYPE IN PLANTS KENDRED, LLC 2023-04-27 — — US disclosed
EP-4164693-A1 NANOLIPOPROTEIN-POLYPEPTIDE CONJUGATES AND COMPOSITIONS, SYSTEMS, AND METHODS USING SAME Genentech, Inc. (US) 2023-04-19 — — EP disclosed
US-11555197-B2 Control of phenotype in plants GREENVENUS, LLC (US) 2023-01-17 — — US disclosed
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