Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TACR3 | P29371 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3049466 | 0.92 | CTSB (0.49) | CTSBALDH1A1KDM4ESMN1; SMN2TACR3 | |
| SCHEMBL3040552 | 0.86 | CTSB (0.43) | CTSBALDH1A1KDM4ESMN1; SMN2TACR3 | |
| SCHEMBL3049806 | 0.82 | CTSB (0.66) | CTSBALDH1A1KDM4ESMN1; SMN2TACR3 | |
| SCHEMBL8285112 | 0.82 | CTSB (0.66) | CTSBALDH1A1KDM4ESMN1; SMN2TACR3 | |
| SCHEMBL3049795 | 0.82 | CTSB (0.66) | CTSBALDH1A1KDM4ESMN1; SMN2TACR3 | |
| SCHEMBL3039920 | 0.81 | CTSB (0.61) | CTSBALDH1A1KDM4ESMN1; SMN2TACR3 | |
| SCHEMBL3048826 | 0.79 | CTSB (0.41) | CTSBALDH1A1KDM4ESMN1; SMN2TACR3 | |
| SCHEMBL3049467 | 0.79 | CTSB (0.62) | CTSBALDH1A1KDM4ESMN1; SMN2TACR3 | |
| SCHEMBL3049462 | 0.79 | CTSB (0.62) | CTSBALDH1A1KDM4ESMN1; SMN2TACR3 | |
| SCHEMBL8286271 | 0.79 | CTSB (0.62) | CTSBALDH1A1KDM4ESMN1; SMN2TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7671032-B2 | HCV NS-3 serine protease inhibitors | MEDIVIR AB (SE) | 2010-03-02 | — | — | US | claimed |
| US-7671032-B2 | HCV NS-3 serine protease inhibitors | MEDIVIR AB (SE) | 2010-03-02 | — | — | US | disclosed |
| EP-1713823-B1 | HCV NS-3 SERINE PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2009-11-11 | — | — | EP | disclosed |
| EP-1713823-A2 | HCV NS-3 SERINE PROTEASE INHIBITORS | Medivir Aktiebolag (SE) | 2006-10-25 | — | — | EP | disclosed |
| WO-2005073195-A2 | HCV NS-3 SERINE PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2005-08-11 | — | — | WO | disclosed |