SCHEMBL304989

SCHEMBL304989

NCCN1C(=O)C=CC1=O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 10/20 0.62
FAAH O00519 5/20 0.62
ALDH1A1 P00352 2/20 0.59
LMNA P02545 2/20 0.59
MAPT P10636 2/20 0.59
NPSR1 Q6W5P4 2/20 0.59
HSP90AA1 P07900 1/20 0.59
TLR9 Q9NR96 1/20 0.59
TP53 P04637 1/20 0.59
PKM P14618 1/20 0.59
HPGD P15428 1/20 0.59
XBP1 P17861 1/20 0.59
MAPK1 P28482 1/20 0.59
HTT P42858 1/20 0.59
RECQL P46063 1/20 0.59
RAB9A P51151 1/20 0.59
SMN1; SMN2 Q16637 1/20 0.59
GPR35 Q9HC97 1/20 0.59
GPR55 Q9Y2T6 1/20 0.59
PTGS1 P23219 7/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18045365 1.00 MGLL (0.62) MGLLFAAHALDH1A1LMNAMAPT
Hydrochloric Acid SCHEMBL354780 0.97 MGLL (0.59) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL1047471 0.84 MGLL (0.71) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL17920257 0.84 MGLL (0.44) MGLLFAAHALDH1A1LMNAMAPT
Hydrochloric Acid SCHEMBL16876819 0.82 MGLL (0.68) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL2919549 0.82 MGLL (0.76) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL145737 0.82 MGLL (0.77) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL14678413 0.82 MGLL (0.77) MGLLFAAHALDH1A1LMNAMAPT
Trifluoroacetic Acid SCHEMBL247137 0.82 PTGS1 (0.44) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL338631 0.80 MGLL (0.77) MGLLFAAHALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2223 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4739360-A1 IMPROVED WOUND DRESSING AND METHOD TO PREPARE IT ResCure GmbH (DE) 2026-05-13 EP claimed
US-12551542-B2 Polymeric nanoparticles that target liver sinusoidal endothelial cells to induce antigen-specific immune tolerance THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-02-17 US claimed
EP-4635501-A2 SAPONIN DERIVATIVES WITH IMPROVED THERAPEUTIC WINDOW Sapreme Technologies B.V. (NL) 2025-10-22 EP claimed
US-20250295800-A1 CONJUGATE OF A SINGLE DOMAIN ANTIBODY, A SAPONIN AND AN EFFECTOR MOLECULE, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, THERAPEUTIC USE OF SAID PHARMACEUTICAL COMPOSITION SAPREME TECH BV (NL) 2025-09-25 US claimed
EP-4003427-B1 SAPONIN DERIVATIVES WITH IMPROVED THERAPEUTIC WINDOW SAPREME TECH BV (NL) 2025-09-17 EP claimed
EP-4596052-A2 THERAPEUTIC COMBINATION OF GALNAC-OLIGONUCLEOTIDE CONJUGATE AND SAPONIN, AND USES THEREOF Sapreme Technologies B.V. (NL) 2025-08-06 EP claimed
EP-4591938-A2 CONJUGATE OF SAPONIN, OLIGONUCLEOTIDE AND GALNAC Sapreme Technologies B.V. (NL) 2025-07-30 EP claimed
EP-4210760-B1 CONJUGATE OF SAPONIN, OLIGONUCLEOTIDE AND GALNAC SAPREME TECH BV (NL) 2025-06-18 EP claimed
EP-4171643-B1 THERAPEUTIC COMBINATION OF GALNAC-OLIGONUCLEOTIDE CONJUGATE AND SAPONIN, AND USES THEREOF SAPREME TECH BV (NL) 2025-06-04 EP claimed
CN-118240030-B COS-coupled PCV2 d-type PCV2 subunit vaccine 山东省农业科学院畜牧兽医研究所 2025-05-23 CN claimed
US-20140170064-A1 METHODS AND COMPOSITIONS FOR RADIOHALOGEN PROTEIN LABELING GENENTECH, INC. (US) 2014-06-19 US claimed
CN-102617852-B Maleimide-polyglutamic acid-aspartic acid polymer and composite thereof, preparation methods for maleimide-polyglutamic acid-aspartic acid polymer and composite thereof, and application of maleimide-polyglutamic acid-aspartic acid polymer and composite thereof UNIV EAST CHINA NORMAL 2013-07-17 CN claimed
CN-103110940-A Click-chemistry-based pneumococcal polysaccharide conjugate vaccine and preparation method thereof INST PROCESS ENG CAS 2013-05-22 CN claimed
CN-102827272-A Folate coupling antibody drug and its preparation method and use WUHAN HUAYAO BIOLOG PHARMACEUTICAL CO LTD 2012-12-19 CN claimed
CN-102666879-A Templated nanoconjugates UNIV NORTHWESTERN 2012-09-12 CN claimed
CN-102626522-A Polypeptide radioactive diagnosis and treatment medicament based on chemotactic factor receptor CXCR4 polypeptide antagonist YANJIANG HAN 2012-08-08 CN claimed
CN-102617852-A Maleimide-polyglutamic acid-aspartic acid polymer and composite thereof, preparation methods for maleimide-polyglutamic acid-aspartic acid polymer and composite thereof, and application of maleimide-polyglutamic acid-aspartic acid polymer and composite thereof UNIV EAST CHINA NORMAL 2012-08-01 CN claimed
EP-2373715-A2 OMEGA-FUNCTIONALIZED POLYMERS, JUNCTION-FUNCTIONALIZED BLOCK COPOLYMERS, POLYMER BIOCONJUGATES, AND RADICAL CHAIN EXTENSION POLYMERIZATION University Of Washington (US) 2011-10-12 EP claimed
WO-2010077678-A2 OMEGA-FUNCTIONALIZED POLYMERS, JUNCTION-FUNCTIONALIZED BLOCK COPOLYMERS, POLYMER BIOCONJUGATES, AND RADICAL CHAIN EXTENSION POLYMERIZATION UNIVERSITY OF WASHINGTON (US) 2010-07-08 WO claimed
US-6274325-B1 USING A FAB'-BIOTIN MATERIAL AND AGGLUTINATABLE PARTICLES WHICH CARRY STREPTAVIDIN OR AVIDIN BOEHRINGER MANNHEIM GMBH (DE) 2001-08-14 US claimed