Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.31 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | MMP7 | P09237 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13741302 | 0.94 | EPHX1 (0.33) | TSHR | |
| SCHEMBL30498975 | 0.86 | — | — | |
| SCHEMBL1546602 | 0.81 | CHRNB2 (0.39) | CHRNB2CHRNA3CHRNA4MMP1MMP3 | |
| SCHEMBL1546601 | 0.81 | CHRNB2 (0.39) | CHRNB2CHRNA3CHRNA4MMP1MMP3 | |
| SCHEMBL30275098 | 0.81 | CHRNB2 (0.39) | CHRNB2CHRNA3CHRNA4MMP1MMP3 | |
| SCHEMBL3316200 | 0.80 | MAPT (0.39) | TSHR | |
| SCHEMBL27286359 | 0.80 | CHRNB2 (0.33) | TSHRCHRNB2CHRNA3CHRNA4CHRNB3 | |
| Hydrochloric Acid SCHEMBL29284073 | 0.79 | CHRNB2 (0.38) | CHRNB2CHRNA3CHRNA4MMP1MMP3 | |
| Hydrochloric Acid SCHEMBL17560384 | 0.79 | CHRNB2 (0.38) | CHRNB2CHRNA3CHRNA4MMP1MMP3 | |
| Piperazine SCHEMBL28081240 | 0.78 | MAPT (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096719-A | Pyridazinylamino derivatives as ALK5 inhibitors | 奇斯药制品公司 | 2023-05-09 | — | — | CN | claimed |
| CN-116096719-A | Pyridazinylamino derivatives as ALK5 inhibitors | 奇斯药制品公司 | 2023-05-09 | — | — | CN | disclosed |