Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.38 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 4/20 | 0.36 |
| ▸ | MAOA | P21397 | 4/20 | 0.36 |
| ▸ | MAOB | P27338 | 4/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1960077 | 0.77 | EZH2 (0.38) | HRH1SLC6A2SLC6A3EZH2TSHR | |
| SCHEMBL8814945 | 0.75 | HRH1 (0.35) | HRH1SLC6A2SLC6A3EZH2TSHR | |
| SCHEMBL11261053 | 0.71 | TDP1 (0.36) | HRH1SLC6A2SLC6A3KDM1ASLC6A4 | |
| SCHEMBL24177909 | 0.70 | SLC6A2 (0.38) | HRH1SLC6A2SLC6A3TRPA1KDM1A | |
| SCHEMBL562024 | 0.69 | SLC6A2 (0.45) | HRH1SLC6A2SLC6A3TSHRSLC6A4 | |
| SCHEMBL451934 | 0.68 | GAA (0.54) | HRH1SLC6A2SLC6A3EZH2TSHR | |
| SCHEMBL10536559 | 0.67 | TRPA1 (0.49) | HRH1SLC6A2SLC6A3TRPA1SLC6A4 | |
| SCHEMBL10536556 | 0.67 | TRPA1 (0.49) | HRH1SLC6A2SLC6A3TRPA1SLC6A4 | |
| SCHEMBL11503115 | 0.67 | TRPA1 (0.46) | HRH1SLC6A2SLC6A3TSHRTRPA1 | |
| SCHEMBL10536550 | 0.67 | TRPA1 (0.49) | HRH1SLC6A2SLC6A3TRPA1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023131116-A1 | CARBONYL BRIDGED HETEROCYCLIC COMPOUND, AND COMPOSITION AND APPLICATION THEREOF | 北京赛特明强医药科技有限公司 | 2023-07-13 | — | — | WO | disclosed |