Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | PGK1 | P00558 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | APP | P05067 | 2/20 | 0.38 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.38 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.34 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 9/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.31 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25297536 | 1.00 | TLR7 (0.42) | TLR7PGK1BACE1APPBACE2 | |
| SCHEMBL14720762 | 0.77 | EGLN1 (0.43) | BACE1APPBACE2EGLN1EGLN3 | |
| SCHEMBL30785541 | 0.73 | TDP1 (0.41) | TLR7PGK1EGLN1EGLN3 | |
| SCHEMBL17498403 | 0.73 | TDP1 (0.41) | TLR7PGK1EGLN1EGLN3 | |
| SCHEMBL25300547 | 0.73 | TLR7 (0.35) | TLR7PGK1EGLN1EGLN3CHRNB2 | |
| SCHEMBL29525656 | 0.73 | IDO1 (0.47) | TLR7BACE1APPBACE2MAP3K7 | |
| SCHEMBL17498439 | 0.73 | IDO1 (0.47) | TLR7BACE1APPBACE2MAP3K7 | |
| SCHEMBL24626311 | 0.72 | HTT (0.37) | EGLN1HTTMAP3K12 | |
| SCHEMBL14720764 | 0.71 | APP (0.44) | APPEGLN1 | |
| SCHEMBL16598517 | 0.70 | ADK (0.47) | APPGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119013265-A | GLUT9 heterocyclic inhibitors for the treatment of disease | 爱尔兰好利恩治疗有限公司 | 2024-11-22 | — | — | CN | disclosed |
| EP-4460496-A1 | HETEROCYCLIC INHIBITORS OF GLUT9 FOR TREATMENT OF DISEASE | Horizon Therapeutics Ireland DAC (IE) | 2024-11-13 | — | — | EP | disclosed |
| WO-2023131868-A1 | HETEROCYCLIC INHIBITORS OF GLUT9 FOR TREATMENT OF DISEASE | HORIZON THERAPEUTICS IRELAND DAC (IE) | 2023-07-13 | — | — | WO | disclosed |