SCHEMBL30499296

SCHEMBL30499296

c1ccc2c(c1)Cc1cc(-c3nc4ccccc4s3)ccc1-2

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP2 O95551 1/20 0.65
RAB9A P51151 9/20 0.53
KDM4E B2RXH2 8/20 0.53
NPC1 O15118 7/20 0.53
MAPT P10636 7/20 0.53
SMN1; SMN2 Q16637 6/20 0.53
ALDH1A1 P00352 5/20 0.53
NFKB1 P19838 4/20 0.53
NFKB2 Q00653 4/20 0.53
RELA Q04206 4/20 0.53
LMNA P02545 3/20 0.53
TP53 P04637 3/20 0.53
HSD17B10 Q99714 3/20 0.53
HPGD P15428 3/20 0.53
PKM P14618 2/20 0.53
APP P05067 6/20 0.52
GLA P06280 2/20 0.51
GAA P10253 2/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22401509 1.00 TDP2 (0.65) TDP2RAB9AKDM4ENPC1MAPT
SCHEMBL15613840 0.87 TDP2 (0.62) TDP2RAB9AKDM4ENPC1MAPT
SCHEMBL11888803 0.83 TDP2 (0.57) TDP2RAB9AKDM4ENPC1MAPT
SCHEMBL13801094 0.82 MAPT (0.46) TDP2RAB9AKDM4ENPC1MAPT
SCHEMBL18892203 0.78 TDP2 (0.46) TDP2RAB9AKDM4ENPC1MAPT
SCHEMBL26107225 0.77 TDP2 (0.57) TDP2RAB9AKDM4ENPC1MAPT
SCHEMBL2139179 0.77 KDM4E (0.54) RAB9AKDM4ENPC1MAPTSMN1; SMN2
SCHEMBL24905146 0.76 TDP2 (0.52) TDP2RAB9AKDM4ENPC1MAPT
SCHEMBL10013462 0.76 APP (0.66) RAB9AKDM4ENPC1MAPTSMN1; SMN2
SCHEMBL22524397 0.76 TDP2 (0.54) TDP2RAB9AKDM4ENPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111263766-B Iridium complex compound, composition containing the compound and solvent, organic electroluminescent element containing the compound, display device and lighting device 三菱化学株式会社 2024-04-02 CN claimed
CN-116655702-A Iridium complex compound and composition containing the same and solvent 三菱化学株式会社 2023-08-29 CN claimed
CN-111263766-B Iridium complex compound, composition containing the compound and solvent, organic electroluminescent element containing the compound, display device and lighting device 三菱化学株式会社 2024-04-02 CN disclosed
CN-116655702-A Iridium complex compound and composition containing the same and solvent 三菱化学株式会社 2023-08-29 CN disclosed