Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.56 |
| ▸ | HTR1A | P08908 | 6/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | DRD4 | P21917 | 3/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28996709 | 0.84 | RAB9A (0.41) | OPRM1HTR1AMEN1ALDH1A1KMT2A | |
| SCHEMBL20025128 | 0.81 | POLB (0.47) | OPRM1TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6302650 | 0.80 | POLB (0.43) | OPRM1TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8486574 | 0.79 | POLB (0.48) | OPRM1CYP2D6TSHRMEN1BLM | |
| SCHEMBL6300484 | 0.79 | POLB (0.43) | OPRM1TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2037515 | 0.79 | SMN1; SMN2 (0.46) | TSHRMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL30876406 | 0.79 | POLB (0.49) | TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL19317381 | 0.79 | POLB (0.49) | TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6958265 | 0.78 | POLB (0.44) | OPRM1TSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2042846 | 0.78 | POLB (0.47) | OPRM1CYP2D6TSHRBLMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096719-A | Pyridazinylamino derivatives as ALK5 inhibitors | 奇斯药制品公司 | 2023-05-09 | — | — | CN | disclosed |