Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | SLC11A2 | P49281 | 3/20 | 0.41 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30174282 | 0.84 | TSHR (0.41) | TSHRPOLBGAASLC11A2PTK2 | |
| SCHEMBL4817433 | 0.77 | TSHR (0.56) | TSHRPOLBGAATDP1MET | |
| SCHEMBL30367869 | 0.77 | TSHR (0.56) | TSHRPOLBGAATDP1MET | |
| SCHEMBL16794627 | 0.73 | PTK2 (0.45) | TSHRPOLBGAASLC11A2PTK2 | |
| SCHEMBL29962532 | 0.73 | PTK2 (0.45) | TSHRPOLBGAASLC11A2PTK2 | |
| SCHEMBL31525602 | 0.72 | POLB (0.45) | TSHRPOLBGAATDP1KDM4E | |
| SCHEMBL30174254 | 0.71 | TSHR (0.46) | TSHRPOLBGAASLC11A2ALKBH3 | |
| SCHEMBL15506087 | 0.71 | GAA (0.41) | TSHRPOLBGAASLC11A2ALKBH3 | |
| SCHEMBL30174212 | 0.71 | SLC11A2 (0.47) | TSHRPOLBGAASLC11A2KDM4E | |
| SCHEMBL15997769 | 0.69 | HSP90AA1 (0.48) | TSHRPOLBGAATDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116437918-A | Pyrazolopyridine compounds as TAM inhibitors | 上海德琪医药科技有限公司 | 2023-07-14 | — | — | CN | disclosed |