Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.39 |
| ▸ | SLC11A2 | P49281 | 2/20 | 0.38 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30499544 | 0.84 | TSHR (0.53) | TSHRKDM4EPOLBGAAPTK2 | |
| SCHEMBL30174254 | 0.81 | TSHR (0.46) | TSHRKDM4EALKBH2EGLN1POLB | |
| SCHEMBL15506087 | 0.78 | GAA (0.41) | TSHRKDM4EPOLBGAATYK2 | |
| SCHEMBL16794627 | 0.77 | PTK2 (0.45) | TSHRKDM4EPOLBGAAMAPK1 | |
| SCHEMBL29962532 | 0.77 | PTK2 (0.45) | TSHRKDM4EPOLBGAAMAPK1 | |
| SCHEMBL28966264 | 0.75 | TSHR (0.44) | TSHRALKBH2EGLN1POLBGAA | |
| SCHEMBL4814573 | 0.75 | TYK2 (0.50) | TSHRKDM4EALKBH2EGLN1POLB | |
| SCHEMBL30367555 | 0.75 | TYK2 (0.50) | TSHRKDM4EALKBH2EGLN1POLB | |
| SCHEMBL6168541 | 0.74 | NOTUM (0.45) | TSHRKDM4EALKBH2EGLN1POLB | |
| SCHEMBL30174171 | 0.74 | MAPK14 (0.47) | KDM4ESLC11A2ALKBH3LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116437918-A | Pyrazolopyridine compounds as TAM inhibitors | 上海德琪医药科技有限公司 | 2023-07-14 | — | — | CN | disclosed |
| CN-115605478-A | Compounds and methods of use | 埃克塞里艾克西斯公司（US） | 2023-01-13 | — | — | CN | disclosed |