Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 4/20 | 0.34 |
| ▸ | BTK | Q06187 | 14/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30499553 | 0.86 | TYRO3 (0.41) | RETBTKTYRO3 | |
| SCHEMBL30499514 | 0.84 | POLB (0.33) | BTKKDM4EHSD17B10 | |
| SCHEMBL30367257 | 0.82 | TYRO3 (0.49) | TYRO3 | |
| SCHEMBL30499523 | 0.79 | TYRO3 (0.41) | BTKTYRO3 | |
| SCHEMBL30499548 | 0.71 | TYRO3 (0.41) | BTKTYRO3 | |
| SCHEMBL30499499 | 0.69 | BTK (0.60) | BTKTYRO3 | |
| SCHEMBL30367412 | 0.68 | TYRO3 (0.62) | TYRO3 | |
| SCHEMBL29052449 | 0.68 | TYRO3 (0.62) | TYRO3 | |
| SCHEMBL30499550 | 0.68 | TYRO3 (0.40) | BTKTYRO3 | |
| SCHEMBL30499531 | 0.68 | TYRO3 (0.44) | BTKTYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116437918-A | Pyrazolopyridine compounds as TAM inhibitors | 上海德琪医药科技有限公司 | 2023-07-14 | — | — | CN | disclosed |