Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAT2A | P31153 | 7/20 | 0.62 |
| ▸ | TNKS | O95271 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | KHK | P50053 | 2/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30499842 | 0.86 | MAT2A (0.65) | MAT2ACDK2GSK3BLIPGKHK | |
| SCHEMBL30499846 | 0.83 | MAT2A (0.39) | MAT2APARP1HSP90AA1 | |
| SCHEMBL29570284 | 0.82 | MAT2A (0.69) | MAT2AMAPT | |
| SCHEMBL22093235 | 0.82 | MAT2A (0.69) | MAT2AMAPT | |
| SCHEMBL31145435 | 0.80 | MAT2A (0.69) | MAT2ALIPGPARP1HSP90AA1 | |
| SCHEMBL22093374 | 0.80 | MAT2A (0.69) | MAT2AMAPTHSP90AA1 | |
| SCHEMBL22093922 | 0.80 | MAT2A (0.69) | MAT2ALIPGPARP1HSP90AA1 | |
| SCHEMBL30499832 | 0.80 | MAT2A (0.69) | MAT2AMAPTHSP90AA1 | |
| SCHEMBL22093366 | 0.77 | MAT2A (1.00) | MAT2AGSK3BLIPGKHK | |
| SCHEMBL29570381 | 0.77 | MAT2A (1.00) | MAT2AGSK3BLIPGKHK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283799-A | Quinazoline methionine adenosyltransferase 2A inhibitors | 南京正大天晴制药有限公司 | 2023-06-23 | — | — | CN | disclosed |