Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22674058 | 0.84 | MEN1 (0.50) | MEN1KMT2ANPC1NPSR1LMNA | |
| SCHEMBL22674061 | 0.84 | MEN1 (0.50) | MEN1KMT2ANPC1NPSR1LMNA | |
| SCHEMBL22673848 | 0.83 | MEN1 (0.49) | MEN1KMT2ANPC1NPSR1LMNA | |
| SCHEMBL22673801 | 0.81 | MEN1 (0.53) | MEN1KMT2ANPC1NPSR1LMNA | |
| SCHEMBL13747276 | 0.74 | KMT2A (0.49) | MEN1KMT2ANPC1NPSR1LMNA | |
| SCHEMBL7398728 | 0.74 | MEN1 (0.45) | MEN1KMT2ANPC1NPSR1ALDH1A1 | |
| SCHEMBL692265 | 0.72 | KMT2A (0.48) | MEN1KMT2ANPC1NPSR1LMNA | |
| SCHEMBL692266 | 0.72 | KMT2A (0.48) | MEN1KMT2ANPC1NPSR1LMNA | |
| SCHEMBL28524412 | 0.72 | MEN1 (0.49) | MEN1KMT2ANPC1HRH2HRH1 | |
| SCHEMBL2429206 | 0.72 | MEN1 (0.49) | MEN1KMT2ANPC1HRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111909133-B | Substituted 1-amino-1H-imidazole-5-carboxamides as inhibitors of brunauer tyrosine kinase | 河南知微生物医药有限公司 | 2023-07-14 | — | — | CN | disclosed |