Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22674061 | 1.00 | MEN1 (0.50) | MEN1KMT2ANPC1FKBP1ALMNA | |
| SCHEMBL22673848 | 0.99 | MEN1 (0.49) | MEN1KMT2ANPC1FKBP1ALMNA | |
| SCHEMBL22673801 | 0.97 | MEN1 (0.53) | MEN1KMT2ANPC1LMNANPSR1 | |
| SCHEMBL13747276 | 0.90 | KMT2A (0.49) | MEN1KMT2ANPC1LMNANPSR1 | |
| SCHEMBL692266 | 0.89 | KMT2A (0.48) | MEN1KMT2ANPC1FKBP1ALMNA | |
| SCHEMBL692265 | 0.89 | KMT2A (0.48) | MEN1KMT2ANPC1FKBP1ALMNA | |
| SCHEMBL30500142 | 0.84 | MEN1 (0.49) | MEN1KMT2ANPC1LMNANPSR1 | |
| SCHEMBL22673922 | 0.82 | KMT2A (0.47) | MEN1KMT2ALMNANPSR1ALDH1A1 | |
| SCHEMBL22673718 | 0.82 | HPGD (0.48) | MEN1KMT2ANPC1LMNAALDH1A1 | |
| SCHEMBL13748014 | 0.81 | LMNA (0.52) | MEN1KMT2ANPC1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228637-A1 | SUBSTITUTED 1-AMINO-1H-IMIDAZOLE-5-CARBOXAMIDE AS BRUTON'S TYROSINE KINASE INHIBITORS | HENAN NORMAL UNIVERSITY (CN) | 2020-11-19 | — | — | WO | disclosed |