Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.48 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20598757 | 1.00 | PIM1 (0.48) | PIM1PIM3ACKR3HIF1AEPAS1 | |
| SCHEMBL30501470 | 0.93 | CSF1R (0.49) | PIM1PIM3ACKR3HIF1AEPAS1 | |
| SCHEMBL20598685 | 0.93 | CSF1R (0.49) | PIM1PIM3ACKR3HIF1AEPAS1 | |
| SCHEMBL20598210 | 0.92 | PIM1 (0.47) | PIM1PIM3ALDH1A1MAPTIRAK4 | |
| SCHEMBL30501459 | 0.92 | PIM1 (0.47) | PIM1PIM3ALDH1A1MAPTIRAK4 | |
| SCHEMBL20598360 | 0.87 | PIM1 (0.46) | PIM1PIM3ALDH1A1MAPTIRAK4 | |
| SCHEMBL30501479 | 0.87 | PIM1 (0.46) | PIM1PIM3ALDH1A1MAPTIRAK4 | |
| SCHEMBL20598423 | 0.85 | PIM1 (0.46) | PIM1PIM3HIF1AEPAS1ALDH1A1 | |
| SCHEMBL20598735 | 0.85 | NTRK1 (0.57) | PIM1PIM3ALDH1A1MAPTIRAK4 | |
| SCHEMBL30501448 | 0.85 | NTRK1 (0.57) | PIM1PIM3ALDH1A1MAPTIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111032642-B | Kinase inhibitors and methods of making and using the same | 里格尔药品股份有限公司 | 2023-07-18 | — | — | CN | disclosed |