Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 2/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.48 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | WDR5 | P61964 | 5/20 | 0.46 |
| ▸ | BACE1 | P56817 | 4/20 | 0.46 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20598685 | 1.00 | CSF1R (0.49) | CSF1RPIM1PIM3ALDH1A1MAPT | |
| SCHEMBL30501336 | 0.93 | PIM1 (0.48) | CSF1RPIM1PIM3ALDH1A1MAPT | |
| SCHEMBL20598757 | 0.93 | PIM1 (0.48) | CSF1RPIM1PIM3ALDH1A1MAPT | |
| SCHEMBL20598665 | 0.92 | PIM1 (0.47) | CSF1RPIM1PIM3ALDH1A1MAPT | |
| SCHEMBL30501377 | 0.92 | PIM1 (0.47) | CSF1RPIM1PIM3ALDH1A1MAPT | |
| SCHEMBL20598222 | 0.87 | PIM1 (0.46) | CSF1RPIM1PIM3ALDH1A1MAPT | |
| SCHEMBL30501423 | 0.87 | PIM1 (0.46) | CSF1RPIM1PIM3ALDH1A1MAPT | |
| SCHEMBL20598587 | 0.85 | CSF1R (0.49) | CSF1RPIM1PIM3ALDH1A1MAPT | |
| SCHEMBL20598482 | 0.85 | PIM1 (0.51) | CSF1RPIM1PIM3ALDH1A1MAPT | |
| SCHEMBL30501501 | 0.85 | PIM1 (0.51) | CSF1RPIM1PIM3ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111032642-B | Kinase inhibitors and methods of making and using the same | 里格尔药品股份有限公司 | 2023-07-18 | — | — | CN | disclosed |