Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 8/20 | 0.59 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | FLT3 | P36888 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | BCL6 | P41182 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.47 |
| ▸ | ULK1 | O75385 | 1/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20598761 | 1.00 | IRAK4 (0.59) | IRAK4IRAK1MEN1KMT2AFLT3 | |
| SCHEMBL20598291 | 0.84 | IRAK4 (0.59) | IRAK4IRAK1MEN1KMT2AMAPT | |
| SCHEMBL30501492 | 0.84 | IRAK4 (0.59) | IRAK4IRAK1MEN1KMT2AMAPT | |
| SCHEMBL20598482 | 0.82 | PIM1 (0.51) | IRAK4IRAK1MAPTALDH1A1NPC1 | |
| SCHEMBL30501501 | 0.82 | PIM1 (0.51) | IRAK4IRAK1MAPTALDH1A1NPC1 | |
| SCHEMBL20598629 | 0.82 | IRAK4 (0.63) | IRAK4IRAK1MEN1KMT2AFLT3 | |
| SCHEMBL30501448 | 0.80 | NTRK1 (0.57) | IRAK4IRAK1MEN1KMT2AMAPT | |
| SCHEMBL20598735 | 0.80 | NTRK1 (0.57) | IRAK4IRAK1MEN1KMT2AMAPT | |
| SCHEMBL20598315 | 0.78 | NPC1 (0.65) | MEN1KMT2AMAPTALDH1A1PKM | |
| SCHEMBL30501370 | 0.78 | NPC1 (0.65) | MEN1KMT2AMAPTALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111032642-B | Kinase inhibitors and methods of making and using the same | 里格尔药品股份有限公司 | 2023-07-18 | — | — | CN | disclosed |