Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 20/20 | 0.74 |
| ▸ | FLT3 | P36888 | 10/20 | 0.74 |
| ▸ | FLT1 | P17948 | 7/20 | 0.74 |
| ▸ | FLT4 | P35916 | 7/20 | 0.74 |
| ▸ | CSF1R | P07333 | 6/20 | 0.74 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.74 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.74 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.74 |
| ▸ | AURKA | O14965 | 2/20 | 0.74 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.74 |
| ▸ | AKT1 | P31749 | 2/20 | 0.74 |
| ▸ | STK3 | Q13188 | 2/20 | 0.74 |
| ▸ | PLK3 | Q9H4B4 | 2/20 | 0.74 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.74 |
| ▸ | TYK2 | P29597 | 1/20 | 0.74 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.74 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.74 |
| ▸ | SGK2 | Q9HBY8 | 1/20 | 0.74 |
| ▸ | KIT | P10721 | 8/20 | 0.67 |
| ▸ | BLK | P51451 | 5/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4092755 | 1.00 | KDR (0.74) | KDRFLT3FLT1FLT4CSF1R | |
| SCHEMBL13873001 | 0.88 | KDR (0.69) | KDRFLT3FLT1FLT4CSF1R | |
| SCHEMBL24232936 | 0.84 | KDR (0.62) | KDRFLT3FLT1FLT4CSF1R | |
| SCHEMBL30501510 | 0.84 | KDR (0.62) | KDRFLT3FLT1FLT4CSF1R | |
| SCHEMBL2819581 | 0.84 | KDR (0.69) | KDRFLT3FLT1FLT4CSF1R | |
| SCHEMBL6073436 | 0.82 | KDR (0.79) | KDRFLT3FLT1FLT4CSF1R | |
| Linifanib SCHEMBL93804 | 0.80 | KDR (1.00) | KDRFLT3FLT1FLT4CSF1R | |
| Linifanib SCHEMBL29375368 | 0.80 | KDR (1.00) | KDRFLT3FLT1FLT4CSF1R | |
| Linifanib SCHEMBL1880038 | 0.80 | KDR (0.98) | KDRFLT3FLT1FLT4CSF1R | |
| SCHEMBL12973352 | 0.80 | KDR (0.56) | KDRFLT3FLT1FLT4CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230145868-A1 | UREA INHIBITORS OF MICRO-RNA | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2023-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230145868-A1 | UREA INHIBITORS OF MICRO-RNA | HNRNPUL1, HNRNPUL2, EFTUD2 | KDR 4367/4885FLT3 3950/4885FLT1 4236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.